H Factors

product on market Capsule Higher Nature 🟢 Safety: 100/100
Brand: Higher Nature
🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 83% of ingredients have research evidence
A Label Compliance Grade

Product Label

Label for H Factors
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Label Data

1 Capsule(s) Serving Size
Other Combinations Product Type
83% Evidence Coverage

Supplement Facts — Evidence Check

15 mg (1071% DV)
📊 11.5× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 15mg
50 mg (3572% DV)
📊 38.5× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 50mg UL 100mg
400 mcg (200% DV)
✅ Within RDA (1.0× RDA of 0.4 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 0.4mg UL 1.0mg
500 mcg (20000% DV)
📊 208.3× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.5mg
10 mg (100% DV)
✅ Within RDA (0.9× RDA of 11 mg) 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 10mg UL 40mg
Tri-Methyl Glycine
750 mg

Other Ingredients

Betaine Monohydrate Capsule Titanium Dioxide Chlorophyllin natural Lithothamnion calcarea Folic Acid Vitamin B6 Zinc Citrate Vitamin B12 Magnesium Stearate Silicon Dioxide Vitamin B6 Vitamin B2

Label Claims — Verification

❓ Nutrient
❓ All Other
❓ Structure/Function
All Other (99% of products) Structure/Function (85% of products) Nutrient (48% of products) No Claim (1% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Directions: Take 2-4 capsules a day with a meal for 12 weeks, then maintain at 1-2 capsules a day. Do not exceed recommended daily intake.

⚠️ Warnings & Precautions

Food supplements should not be used as a substitute for a varied and balanced diet and healthy lifestyle.

Warning: B vitamins may turn urine bright yellow - this is normal. Long term intakes of this amount of Vitamin B6 may lead to mild tingling and numbness.

Storage: Store in a cool, dry place out of reach of children.

🧪 Formulation Notes

Free From: Artificial colours, flavourings or preservatives, dairy products, gluten, lactose, salt, soya, wheat, yeast.

Body health Advanced formula Optimal benefit

Homocysteine & heart nutrients

Vegetarian and vegan

Vitamins B6 and B12, folic acid and TMG help support healthy homocysteine levels

Additional Information

NRV = Nutrient Reference Value

This product has not been tested on animals.

Storage: Store in a cool, dry place out of reach of children.

Product Details

UPC / SKU 5 031013 102790
DSLD Entry Date 2020-06-24
Product Type Other Combinations
Form Capsule
Brand Higher Nature
DSLD ID 224695
Data Updated 2026-04-11

Research Evidence

22 Research Sources
49 Avg Quality Score
8 Rct
4 Meta Analysis
4 Clinical Trial
3 Systematic Review
1 Cochrane Review
1 Regulatory Source
B Effect of vitamin B2, vitamin C, vitamin D, vitamin E and folic acid in adults with essential hypertension: a systematic review and network meta-analysis
Systematic Review BMJ open 2024
PubMed DOI
B Effect of Vitamin B2 supplementation on migraine prophylaxis: a systematic review and meta-analysis
Meta Analysis Nutritional neuroscience 2022
PubMed DOI
B Supplementary vitamin E, selenium, cysteine and riboflavin for preventing kwashiorkor in preschool children in developing countries
Systematic Review The Cochrane database of systematic reviews 2010
PubMed DOI Cochrane
B Riboflavin supplements for blood pressure lowering in adults.
Cochrane Review The Cochrane database of systematic reviews
PubMed DOI Cochrane
B Associations of dietary vitamin B1, vitamin B2, vitamin B6, and vitamin B12 with the risk of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2022
PubMed DOI
C Prophylaxis of migraine headaches with riboflavin: A systematic review
Systematic Review Journal of clinical pharmacy and therapeutics 2017
PubMed DOI
C Medium-dose riboflavin as a prophylactic agent in children with migraine: a preliminary placebo-controlled, randomised, double-blind, cross-over trial
Rct Cephalalgia : an international journal of headache 2010
PubMed DOI
C The efficacy of 2 different phakic intraocular lens implant in keratoconus as an isolated procedure or combined with collagen crosslinking and intra-stromal corneal ring segments: a systematic review and meta-analysis
Meta Analysis International ophthalmology 2023
PubMed DOI
C Epithelium-off photochemical corneal collagen cross-linkage using riboflavin and ultraviolet a for keratoconus and keratectasia: a systematic review and meta-analysis
Meta Analysis The ocular surface 2014
PubMed DOI
C Improvement of migraine symptoms with a proprietary supplement containing riboflavin, magnesium and Q10: a randomized, placebo-controlled, double-blind, multicenter trial
Rct The journal of headache and pain 2015
PubMed DOI
View all evidence for Riboflavin →

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