Serotone 5HTP 50 mg

product on market Capsule Higher Nature 🟢 Safety: 100/100
Brand: Higher Nature
🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Capsule(s) Serving Size
Botanical with Nutrients Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

15 mg NE (94% DV)
✅ 1.1× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 15mg UL 35mg
5 mg (357% DV)
📊 3.8× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 5mg UL 100mg
50 mcg (25% DV)
✅ Within RDA (0.1× RDA of 0.4 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 0.05mg UL 1.0mg
25 mcg (50% DV)
✅ Within RDA (0.8× RDA of 0.03 mg) 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.025mg
2.5 mg (25% DV)
✅ Within RDA (0.2× RDA of 11 mg) 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 2.5mg UL 40mg
50 mg
📊 Market median: 100.0mg (116 products) 📚 15 studies (Tier A: 0, B: 3)
This product: 50mg

Other Ingredients

Rice Bran Hydroxypropyl Methylcellulose L-5-Hydroxytryptophan Niacin Zinc Citrate Pyridoxal 5-Phosphate Pyridoxine Hydrochloride Silicon Dioxide Magnesium Stearate Folic Acid Biotin

Label Claims — Verification

❓ Nutrient
❓ All Other
❓ Structure/Function
All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

Directions: Adults take 1-2 capsules a day preferably before bed with a carbohydrate snack, or as your health professional advises. Do not exceed recommended daily intake.

⚠️ Warnings & Precautions

Do not exceed recommended daily intake. Food supplements should not be used as a substitute for a varied and balanced diet and healthy lifestyle.

Warning: Consult your doctor if under medical supervision or taking prescribed medications. Not advisable if pregnant or if taking antidepressants.

Can cause drowsiness; do not drive or operate machinery if affected. If gastro-intestinal discomfort occurs, reduce intake.

Storage: Store in a cool, dry, steam free environment out of reach of children.

🧪 Formulation Notes

Does not contain: Artificial colours, flavourings or preservatives, corn, dairy products, gluten, lactose, maize, salt, soya, sugar, wheat, yeast.

Suitable for vegetarians and vegans. This product is not tested on animals.

5HTP is an amino acid needed to produce serotonin. Vits B3 & B6 contribute to normal psychological function.

Additional Information

Ultimate nutrition

Storage: Store in a cool, dry, steam free environment out of reach of children.

Product Details

UPC / SKU 5 031013 100093
DSLD Entry Date 2020-04-23
Product Type Botanical with Nutrients
Form Capsule
Brand Higher Nature
DSLD ID 217155
Data Updated 2026-04-11

Research Evidence

241 Research Sources
55 Avg Quality Score
113 Meta Analysis
75 Systematic Review
32 Rct
11 Clinical Trial
3 Other
3 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
PubMed DOI Cochrane
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013
PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014
PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024
PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010
PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010
PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014
PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020
PubMed DOI Cochrane
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019
PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016
PubMed DOI
View all evidence for Niacin →

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