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H Factors

product on market Capsule Higher Nature Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 83% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This profile contains B vitamins and zinc, which are supported by strong evidence for supporting cellular energy metabolism and immune function. These nutrients play essential roles in DNA synthesis and neurological health. The overall evidence coverage for this specific combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for H Factors
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
Other Combinations
Product Type
83%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

15 mg (1071% DV)
11.5× RDA — above typical dose 13 studies (A:0, B:1)
50 mg (3572% DV)
38.5× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
400 mcg (200% DV)
Within RDA (1.0× RDA) 226 studies (A:10, B:105)
500 mcg (20000% DV)
208.3× RDA — above typical dose 139 studies (A:1, B:44)
10 mg (100% DV)
Within RDA (0.9× RDA) 263 studies (A:6, B:134)
Tri-Methyl Glycine
750 mg

Other Ingredients

Betaine Monohydrate Capsule Titanium Dioxide Chlorophyllin natural Lithothamnion calcarea Folic Acid Pyridoxal 5-Phosphate Zinc Citrate Methylcobalamin Magnesium Stearate Silicon Dioxide Pyridoxine Hydrochloride Riboflavin
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take 2-4 capsules a day, with a meal, for 12 weeks, then maintain at 1-2 capsules a day. Do not exceed recommended daily intake.

Warnings & Precautions

Food supplements should not be used as a substitute for a varied and balanced diet and healthy lifestyle.

Warning: B vitamins may turn urine bright yellow - this is normal. Long term intakes of this amount of vitamin B6 may lead to mild tingling and numbness.

Storage: Store in a cool, dry, steam free environment out of reach of children.

Formulation Notes

Does not contain: Artificial colours, flavourings or preservatives, dairy products, gluten, lactose, salt, soya, wheat, yeast.

Suitable for vegetarians and vegans. This product is not tested on animals.

Homocysteine & heart nutrients

Vitamins B6 and B12, folic acid and TMG help support healthy homocysteine levels

Additional Information

Ultimate nutrition

Storage: Store in a cool, dry, steam free environment out of reach of children.

Metadata

Product Details

UPC / SKU5 031013 102806
DSLD Entry Date2020-05-22
Product TypeOther Combinations
FormCapsule
BrandHigher Nature
DSLD ID216985
Data Updated2026-04-11
Research

Research Evidence

22
Research Sources
49
Avg Quality
8
Rct
4
Meta Analysis
4
Clinical Trial
3
Systematic Review
1
Cochrane Review
1
Regulatory Source
B Effect of vitamin B2, vitamin C, vitamin D, vitamin E and folic acid in adults with essential hypertension: a systematic review and network meta-analysis
Systematic Review BMJ open 2024 PubMed DOI
B Effect of Vitamin B2 supplementation on migraine prophylaxis: a systematic review and meta-analysis
Meta Analysis Nutritional neuroscience 2022 PubMed DOI
B Supplementary vitamin E, selenium, cysteine and riboflavin for preventing kwashiorkor in preschool children in developing countries
Systematic Review The Cochrane database of systematic reviews 2010 PubMed DOI
B Riboflavin supplements for blood pressure lowering in adults.
Cochrane Review The Cochrane database of systematic reviews PubMed DOI
B Associations of dietary vitamin B1, vitamin B2, vitamin B6, and vitamin B12 with the risk of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2022 PubMed DOI
C Prophylaxis of migraine headaches with riboflavin: A systematic review
Systematic Review Journal of clinical pharmacy and therapeutics 2017 PubMed DOI
C Medium-dose riboflavin as a prophylactic agent in children with migraine: a preliminary placebo-controlled, randomised, double-blind, cross-over trial
Rct Cephalalgia : an international journal of headache 2010 PubMed DOI
C The efficacy of 2 different phakic intraocular lens implant in keratoconus as an isolated procedure or combined with collagen crosslinking and intra-stromal corneal ring segments: a systematic review and meta-analysis
Meta Analysis International ophthalmology 2023 PubMed DOI
C Epithelium-off photochemical corneal collagen cross-linkage using riboflavin and ultraviolet a for keratoconus and keratectasia: a systematic review and meta-analysis
Meta Analysis The ocular surface 2014 PubMed DOI
C Improvement of migraine symptoms with a proprietary supplement containing riboflavin, magnesium and Q10: a randomized, placebo-controlled, double-blind, multicenter trial
Rct The journal of headache and pain 2015 PubMed DOI
View all evidence for Riboflavin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.