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Ortho Sleep

product on market Capsule AOR Advanced Orthomolecular Research Advanced Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 71% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

This formula combines L-Theanine, GABA, and 5-HTP, which are supported by moderate evidence for promoting relaxation and sleep quality. Lemon balm and valerian root are also included, with research suggesting they may reduce sleep latency. Overall, these ingredients are widely studied for their calming effects on the central nervous system.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Ortho Sleep
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
71%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Lemon Balm (Melissa officinalis L.) aerial parts extract
300 mg
200 mg
Market median: 200.0mg (358 products) 9 studies (A:0, B:2)
Market median: 300.0mg (214 products) 25 studies (A:0, B:6)
GABA
100 mg
Market median: 100.0mg (116 products) 18 studies (A:0, B:3)
Market median: 250.0mg (60 products) 7 studies (A:0, B:1)
3 mg
Market median: 3.0mg (984 products) 240 studies (A:2, B:109)

Other Ingredients

Capsule Maltodextrin Silicon Dioxide Gum Arabic Sodium Stearyl Fumarate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take 2 capsules before bedtime with/without food or as directed by a qualified health care practitioner.

Warnings & Precautions

Do not use if safety seal is broken

Warning: Do not use if pregnant or breastfeeding. Consult a health care practitioner prior to use if you have a medical condition or if you’re using other medications.

Keep out of reach of children.

Caution: Do not drive or use machinery for 5 hours after taking Ortho Sleep, exercise caution if operating heavy machinery, driving a motor vehicle or involved in activities requiring mental alertness. Hypersensitivity (e.g. allergy) has been known to occur, in which case, discontinue use and consult a healthcare provider.

To report a serious adverse event or obtain product information, call 1-866-215-0450

Formulation Notes

GMP Manufacturing Quality assured Independent testing

Discussion: Ortho Sleep is a comprehensive formula including the most powerful and clinically studied natural ingredients available, including melatonin, GABA, valerian root and lemon balm extract.

Promotes normal, calm and peaceful sleep.

Ortho Sleep With Cyracos

Promotes restful sleep

Vegan

Non-GMO Gluten free

AOR guarantees that all ingredients have been declared on the label.

Made without wheat, gluten, nuts, peanuts, sesame seeds, sulfites, mustard, soy, dairy, eggs, fish, shellfish or any animal byproduct.

Additional Information

Store tightly sealed in a cool, dry place

Product of Canada

Metadata

Product Details

UPC / SKU6 24917 08186 2
DSLD Entry Date2020-03-24
Product TypeOther Combinations
FormCapsule
DSLD ID214855
Data Updated2026-04-11
Research

Research Evidence

33
Research Sources
52
Avg Quality
13
Systematic Review
10
Rct
7
Meta Analysis
1
Regulatory Source
1
Openfda Safety
B Non-pharmacological interventions for sleep promotion in the intensive care unit
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Valerian Root in Treating Sleep Problems and Associated Disorders-A Systematic Review and Meta-Analysis
Meta Analysis Journal of evidence-based integrative medicine 2020 PubMed DOI
B Effectiveness and safety of oral sedation in adult patients undergoing dental procedures: a systematic review
Systematic Review BMJ open 2021 PubMed DOI
B Valerian for anxiety disorders
Systematic Review The Cochrane database of systematic reviews 2006 PubMed
B Herbal medicine for insomnia: A systematic review and meta-analysis
Meta Analysis Sleep medicine reviews 2015 PubMed DOI
B Effects of Dietary Supplementation in Patients with Restless Legs Syndrome: A Systematic Review
Systematic Review Nutrients 2024 PubMed DOI
B Valerian for sleep: a systematic review and meta-analysis
Meta Analysis The American journal of medicine 2006 PubMed
B Herbal Remedies and Their Possible Effect on the GABAergic System and Sleep
Systematic Review Nutrients 2021 PubMed DOI
B Herbal medicines in children with attention deficit hyperactivity disorder (ADHD): A systematic review
Systematic Review Complementary therapies in medicine 2017 PubMed DOI
B Effectiveness of Valerian on insomnia: a meta-analysis of randomized placebo-controlled trials
Meta Analysis Sleep medicine 2010 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.