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Vitamin B Complex

product on market Tablet or Pill up&up Safety: 95/100
95/100

This product looks safe

  • Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • 88% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This complex contains B vitamins that support energy metabolism and neurological function. Strong research evidence supports the role of thiamine, riboflavin, and folic acid in cellular health. The ingredient profile maintains a high safety score, indicating a low risk of adverse effects for most users.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)

Label

Product Label

Label for Vitamin B Complex
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
Vitamin
Product Type
88%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

50 mg (3333% DV)
41.7× RDA — above typical dose 76 studies (A:0, B:33)
50 mg (2941% DV)
38.5× RDA — above typical dose 13 studies (A:0, B:1)
50 mg (250% DV)
Exceeds UL by 1.4× (UL: 35 mg) 196 studies (A:5, B:63)
50 mg (2500% DV)
38.5× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
400 mcg (100% DV)
Within RDA (1.0× RDA) 226 studies (A:10, B:105)
50 mcg (833% DV)
20.8× RDA — above typical dose 139 studies (A:1, B:44)
50 mcg (17% DV)
1.7× RDA — within safe limits 27 studies (A:0, B:11)
50 mg (500% DV)
10.0× RDA — above typical dose 2 studies — no high-quality reviews

Other Ingredients

Dicalcium Phosphate Microcrystalline Cellulose Pyridoxine Hydrochloride Calcium Pantothenate Riboflavin Niacinamide Thiamine Mononitrate Croscarmellose Sodium Stearic Acid Silicon Dioxide Magnesium Stearate Dextrin Dextrose Lecithin Folic Acid Sodium Carboxymethylcellulose Sodium Citrate Cyanocobalamin Biotin
Claims

Label Claims — Verification

Unverified All Other
Unverified Approved Health
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use: Adults, take one tablet daily with the meal of your choice.

Warnings & Precautions

If you are pregnant or nursing a baby, ask a doctor before using this product.

Keep out of reach of children.

Formulation Notes

CONTAINS: SOY

This product contains 100% of the US reference daily intake (RDI) of folate.

No artificial colors have been added to this formula, the product may vary in color.

GLUTEN FREE

Additional Information

ACTUAL SIZE

high potency helps support energy metabolism and nervous system health*

B

up&up(R)

ENERGY METABOLISM*

094 02 2114 : 4Y815 UW F2

ENERGY METABOLISM* Vitamin B complex consists of several essential nutrients needed by the body. This complex of B vitamins plays a role in well-being and energy metabolism and assists nerve function.*

Store at room temperature (59(0)-86(0)F).

This product is formulated per official U.S. Pharmacopeia (USP) standards to meet quality, potency and disintegration or dissolution requirements.

Adequate folate in healthful diets may reduce a woman's risk of having a child with a brain or spinal cord birth defect.

Each tablet in this bottle is clear coated for easy swallowing.

EXP11/13 2HN1695

ID482463

Metadata

Product Details

UPC / SKU0 70030 62498 9
DSLD Entry Date2013-04-25
Product TypeVitamin
FormTablet or Pill
Brandup&up
DSLD ID20200
Data Updated2026-04-11
Research

Research Evidence

100
Research Sources
56
Avg Quality
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013 PubMed DOI
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023 PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022 PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022 PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020 PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021 PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022 PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023 PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004 PubMed
View all evidence for Thiamine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.