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Immune + Energy Fresh Citrus

product on market Other (e.g. tea bag) Culturelle Pro-Well Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Vitamin C and B vitamins like thiamine and riboflavin are supported by strong evidence for their roles in immune function and energy metabolism. These nutrients facilitate cellular energy production and antioxidant defense. However, overall evidence coverage for this specific ingredient profile is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Immune + Energy Fresh Citrus
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Packet(s)
Serving Size
Other Combinations
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
5 Calorie(s)
Total Carbohydrates
1 Gram(s) (1% DV)
Vitamin C
90 mg (100% DV)
1.2 mg (100% DV)
Within RDA (1.0× RDA) 76 studies (A:0, B:33)
1.3 mg (100% DV)
Within RDA (1.0× RDA) 13 studies (A:0, B:1)
5.6 mg (35% DV)
Within RDA (0.4× RDA) 196 studies (A:5, B:63)
1.7 mg (100% DV)
1.3× RDA — within safe limits 114 studies (A:3, B:35)
2.4 mcg (100% DV)
Within RDA (1.0× RDA) 139 studies (A:1, B:44)
5 mg (100% DV)
Within RDA (1.0× RDA) 2 studies — no high-quality reviews

Other Ingredients

Fructooligosaccharides Citric Acid Malic Acid Natural & Artificial flavor Sucralose Sucrose Silicon Dioxide Maltodextrin
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions for 12 years of age and older: For daily use, take one (1) single serve packet per day. Simply mix one packet with 8 or more ounces of water and enjoy. More water equals lighter flavor. For optimal results, continued daily use is suggested.

Warnings & Precautions

While there are no dairy-derived ingredients in the product, it is produced in a facility that also handles dairy ingredients.

Tamper Evident: Product is sealed within packets. Do not use if any part of the packet is torn, open or damaged.

When first taking Culturelle, you may experience minor bloating, gas or intestinal gurgling which should subside with continued use. Consult your physician if symptoms persist after two weeks.

For questions, concerns or to report an adverse event, please call (800) 722-3476.

Keep out of reach of children.

Inform a healthcare professional before starting any dietary supplement, particularly if there is a know immune-compromised condition.

Formulation Notes

Lactobacillus rhamnosus GG helps support your natural immune defenses, by working in your body’s core where 70% of your immune system resides. With a specially formulated blend of vitamin C & energy-inducing B vitamins to deliver sustained energy levels – caffeine-free! Contains 100% of the daily value of vitamins C, B1, B2, B5, B6 and B12. Also an excellent source of vitamin B3.

With a specially formulated blend of vitamin C & energy-inducing B vitamins to deliver sustained energy levels – caffeine-free!

Exclusively Powered with the LGG Probiotic. The Single-Strain Super Probiotic. Lactobacillus rhamnosus GG (LGG) is the most clinically proven effective strain.

You can trust Culturelle, the expert in probiotics, because it is the only brand with 100% pure LGG.

Only Culturelle Combines: LGG 100% of the #1 proven effective probiotic.

Dairy-free. Gluten-free. Sugar-free.

B-vitamins support energy through metabolic function.

Meets the FDA's guidelines for gluten-free.

Contains sucrose which adds a dietarily insignificant amount of sugar. Not a reduced calorie food.

Contains none of the following: Artificial dyes, artificial preservatives, dairy, lactose, milk, yeast, wheat, gluten or soy.

Exclusively with the #1 proven effective probiotic LGG

With a special blend of vitamin C & energy-inducing B vitamins for sustained energy

Additional Information

A great tasting water enhancer that easily transforms your water into an infusion of immune- and energy-supporting hydration. It works naturally with your body to help keep you feeling your best and going strong all day long. Promotes Immune Support + All-day Energy!

It’s the only one you need to help support good digestion and immune health.

Purity potency guaranteed Dairy-free. Gluten-free. Sugar-free.

Guaranteed potency through the expiration date vs. just the time of manufacture. #1 Pharmacist Recommended Probiotic Brand.

Based on the studies of Lactobacillus rhamnosus GG for a range of benefits throughout the lifespan. Guaranteed potency through date on box when stored as directed. Based on the 2017 Pharmacy Times OTC Survey. Among leading brands.

Storage Instructions: Store Culturelle in a cool, dry place away from direct sunlight.

We certify that our products meet the highest standards of purity and potency.

COBM4486

The expert in probiotics

Helps support your natural immune defenses

Keeps you going strong all day long Natural and artificial flavors

Metadata

Product Details

UPC / SKU0 49100 40049 5
DSLD Entry Date2018-10-25
Product TypeOther Combinations
FormOther (e.g. tea bag)
DSLD ID182545
Data Updated2026-04-11
Research

Research Evidence

371
Research Sources
54
Avg Quality
148
Meta Analysis
82
Systematic Review
71
Rct
62
Clinical Trial
2
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Other
1
Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024 PubMed DOI
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021 PubMed DOI
View all evidence for Vitamin C →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.