Liquid Joint Elixir by Esmond Natural — Ingredients, Evidence & Safety

🟢 100/100

This product looks safe

No ingredients exceed tolerable upper intake levels
32% of ingredients have research evidence

A Label Compliance Grade

Product Label

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Label Data

1 fl. Oz. Serving Size

16 Servings

Other Combinations Product Type

32% Evidence Coverage

Supplement Facts — Evidence Check

Calories

20 Calorie(s)

Calories from Fat

Total Fat

Saturated Fat

Cholesterol

Sodium

Total Carbohydrates

5 Gram(s) (2% DV)

Dietary Fiber

1 Gram(s)

Sugar

3.3 Gram(s)

Protein

Glucosamine

1500 mg

📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)

This product: 1500mg

Chondroitin

1000 mg

📊 Market median: 600.0mg (79 products) 📚 24 studies (Tier A: 0, B: 6)

This product: 1000mg

MSM

500 mg

📊 Market median: 1000.0mg (2 products)

This product: 500mg

Vitamin C

120 mg (200% DV)

Vitamin D3

400 IU (100% DV)

✅ Within RDA (0.7× RDA of 0.015 mg) 📚 604 studies (Tier A: 16, B: 251)

RDA 0.015mg This product: 0.01mg UL 0.1mg

Collagen

100 mg

📊 Market median: 20.0mg (931 products) 📚 233 studies (Tier A: 1, B: 90)

This product: 100mg

Hyaluronic Acid

50 mg

📊 Market median: 100.0mg (173 products)

Median 100.0mg This product: 50mg

Lycopene

50 mg

📊 Market median: 10.0mg (35 products) 📚 5 studies (Tier A: 0, B: 2)

This product: 50mg

Zinc

10 mg (67% DV)

✅ Within RDA (0.9× RDA of 11 mg) 📚 258 studies (Tier A: 6, B: 134)

RDA 11mg This product: 10mg UL 40mg

Other Ingredients

filtered Water Glucosamine Sulfate Chondroitin Sulfate Methylsulfonyl Methane Ascorbic Acid Cholecalciferol Collagen Lycopene Invert Sugar Pectin Guar Gum Aloe Vera Zinc Citric Acid natural Pineapple flavor natural Mango flavor Potassium Sorbate

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (100% of products) Structure/Function (90% of products) Nutrient (17% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Directions: Shake well before use. Take 2 tablespoons (1 fl. oz.) daily on an empty stomach, preferably in the morning or as directed by your health care professional.

⚠️ Warnings & Precautions

Warning: If you are pregnant, nursing, taking any medications or planning any medical procedure, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of reach of children.

Tamper Resistant: Do not use if imprinted seal under cap is broken or missing.

🧪 Formulation Notes

MSM and vitamin D3 fortified

Additional Information

Made in USA

BPA free

Mango & pineapple flavors

Liquid Joint Elixir is formulated to promote healthy bone structure and function. It supports joint functions and can also prevent nocturnal leg muscle cramps. Vitamin D3 is essential for calcium absorption and vital for bone growth and maintenance.

Refrigerate after opening.

Store in a dry place and avoid excessive heat.

Good Manufacturing Practices GMP

Natural Products Association Certified

Product Details

UPC / SKU 6 41399 10801 6

DSLD Entry Date 2018-07-25

Product Type Other Combinations

Form Liquid

Brand Esmond Natural

DSLD ID 179116

Data Updated 2026-04-11

Research Evidence

14 Research Sources

50 Avg Quality Score

9 Rct

3 Clinical Trial

1 Systematic Review

1 Guideline

B Dressings and topical agents containing hyaluronic acid for chronic wound healing

Systematic Review The Cochrane database of systematic reviews 2023

PubMed DOI

B Effect of laughter exercise versus 0.1% sodium hyaluronic acid on ocular surface discomfort in dry eye disease: non-inferiority randomised controlled trial

Rct BMJ (Clinical research ed.) 2024

PubMed DOI

B Expert consensus on hyaluronic acid injections for knee osteoarthritis: a patient-centered approach.

Guideline Aging clinical and experimental research 2026

PubMed DOI

C The Effects of Dietary Supplementation with Collagen and Vitamin C and Their Combination with Hyaluronic Acid on Skin Density, Texture and Other Parameters: A Randomised, Double-Blind, Placebo-Controlled Trial

Rct Nutrients 2024

PubMed DOI

C Effects of ozone combined with articular injection of sodium hyaluronate on patients with knee osteoarthritis and their inflammatory factors and hemorheological indices.

Rct African health sciences

PubMed DOI

C The effect of oral low molecular weight liquid hyaluronic acid combination with glucosamine and chondroitin on knee osteoarthritis patients with mild knee pain: An 8-week randomized double-blind placebo-controlled trial.

Rct Medicine

PubMed DOI

C Liquid combination of hyaluronan, glucosamine, and chondroitin as a dietary supplement for knee osteoarthritis patients with moderate knee pain: A randomized controlled study.

Rct Medicine

PubMed DOI

C Oral preparation of hyaluronic acid, chondroitin sulfate, N-acetylglucosamine, and vitamin C improves sexual and urinary symptoms in participants with recurrent urinary tract infections: a randomized crossover trial.

Rct The journal of sexual medicine

PubMed DOI

C PMCF Study to Evaluate Performance and Safety of 'Hyaluronic Acid (HA)-Based Eyedrops' Used to Relieve Dry Eye Symptoms

Clinical Trial ClinicalTrials.gov 2022

ClinicalTrials.gov

C Effect of Hyaluronic Acid Oral Supplementation on Sexual and Urinary Symptoms of Women With Recurrent Urinary Tract Infections

Clinical Trial ClinicalTrials.gov 2022

ClinicalTrials.gov

View all evidence for Hyaluronic Acid →