🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 75% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Capsule(s) Serving Size
30 Servings
Other Combinations Product Type
75% Evidence Coverage

Supplement Facts — Evidence Check

400 IU (100% DV)
✅ Within RDA (0.7× RDA of 0.015 mg) 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.01mg UL 0.1mg
400 mcg (100% DV)
✅ Within RDA (1.0× RDA of 0.4 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 0.4mg UL 1.0mg
15 mg (100% DV)
✅ 1.4× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 15mg UL 40mg
Sodium
5 mg (1% DV)
Syno-Portin(R) Complex
125 mg
📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)
This product: 100mg
📊 Market median: 600.0mg (79 products) 📚 24 studies (Tier A: 0, B: 6)
This product: 100mg
📊 Market median: 450.0mg (254 products) 📚 240 studies (Tier A: 0, B: 100)
This product: 25mg

Other Ingredients

vegetable capsule Sodium Bicarbonate Citric Acid Magnesium Stearate Silicon Dioxide

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (85% of products) Nutrient (70% of products) Approved Health (4% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Recommended use: Take 1 capsule daily with meal.

⚠️ Warnings & Precautions

If you are allergic to any of these ingredients, or are pregnant or nursing, consult a doctor before taking this or any other dietary supplement.

Keep out of reach of children.

Do not use if seal is broken.

SAFETY SEALED PACKAGE FOR YOUR PROTECTION. DO NOT USE IF INDIVIDUAL SEALS ARE BROKEN.

Additional Information

Do not expose to excessive heat, humidity or direct sunlight.

Revolutionary formula for bone health Nikken OsteoDenx is a unique preparation because it supports both aspects of bone health - the release and absorbance of vital mineral compounds, and the formation of new, strong bone tissue to replace absorbed material. Ordinary supplements merely provide minerals such as calcium and phosphorus in an effort to replace what is depleted every day. OsteoDenx is different: it is designed to complement the body’s natural tissue growth mechanisms and to help support the physical process of preserving bone density. Good bone health needs to be maintained daily. OsteoDenx can help. Ordinary supplements do not include a method for sending the active components where needed. Only OsteoDenx features Syno-PortinTM technology. This patented system takes this bone health support to the specific target site — the joint area, or synovium — for improved bioavailability. Syno-portin technology promotes the optimal balance of these materials within bones and joints to help maintain bone density and support the structure and integrity of joint cartilage. OsteoDenx is made from all-natural ingredients, and produced using an extensive purification process. It is designed to support bone health in men and women — important at every stage of life. Bone health requires a diet that includes calcium, and regular practice of weight-bearing exercise. Nikken recommends that OsteoDenx and Nikken CalDenx® (calcium supplement) should both be taken on a regular basis to help ensure strong, healthy bones.

Store at room temperature, in a cool dry place.

NIKKEN(R)

#15583 US Last revised: 4/10

Product Details

UPC / SKU #15583
DSLD Entry Date 2012-07-25
Product Type Other Combinations
Form Capsule
Brand Nikken
DSLD ID 11291
Data Updated 2026-04-11

Research Evidence

872 Research Sources
53 Avg Quality Score
309 Meta Analysis
309 Clinical Trial
111 Rct
71 Systematic Review
55 Guideline
4 Cochrane Review
4 Regulatory Source
2 Other
2 Narrative Review
2 Observational
1 Openfda Safety
A Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis
Meta Analysis The Cochrane database of systematic reviews 2009
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2014
A Vitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older men
Meta Analysis The Cochrane database of systematic reviews 2014
A Vitamin D supplementation for prevention of cancer in adults
Meta Analysis The Cochrane database of systematic reviews 2014
A Interventions for preventing falls in older people in care facilities and hospitals
Meta Analysis The Cochrane database of systematic reviews 2018
A Drugs for preventing lung cancer in healthy people
Meta Analysis The Cochrane database of systematic reviews 2020
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2011
A High prevalence of vitamin D deficiency in Asia: A systematic review and meta-analysis
Meta Analysis Critical reviews in food science and nutrition 2023
A The effect of vitamin D supplementation on depressive symptoms in adults: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2023
A Interventions for preventing falls in older people living in the community
Meta Analysis The Cochrane database of systematic reviews 2009
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