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Calcium Citrate + Magnesium

product on market Tablet or Pill Nature Made Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 56% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Calcium, magnesium, and vitamin D3 are supported by strong evidence for maintaining bone density and skeletal health. Vitamin B6 and zinc contribute to immune function and metabolic processes, though evidence for general supplementation is more moderate. This profile maintains a high safety score with no significant concerns noted.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Calcium Citrate + Magnesium
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Tablet(s)
Serving Size
Multi-Vitamin and Mineral (MVM)
Product Type
56%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

800 IU (200% DV)
1.3× RDA — within safe limits 608 studies (A:16, B:251)
10 mg (500% DV)
7.7× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
Calcium
500 mg (50% DV)
80 mg (20% DV)
Within RDA (0.2× RDA) 316 studies (A:8, B:159)
10 mg (67% DV)
Within RDA (0.9× RDA) 263 studies (A:6, B:134)
1 mg (50% DV)
1.1× RDA — within safe limits 37 studies (A:0, B:11)
1 mg (50% DV)
Within RDA (0.4× RDA) 9 studies — no high-quality reviews
Sodium
5 mg (1% DV)
1 mg
Market median: 3.0mg (58 products) 3 studies — no high-quality reviews

Other Ingredients

Cellulose Gel Talc Croscarmellose Sodium Hydroxypropyl Methylcellulose Magnesium Stearate Polyethylene Glycol Gelatin Corn Starch
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Helps build strong bones and teeth and can be taken without food

Dosage: Suggested Use: Take two tablets 1 to 2 times daily

Warnings & Precautions

Magnesium be used with caution when combined with: - Antibiotics - Osteoporosis medications (bisphosphonates)

Caclium should be used with caution when combined with: - Osteoporosis medications (bisphosphonates) - Antibiotics - Blood pressure medications - Thyroid medication

Zinc should be avoided when taking: - Current research does not indicate that this supplement should be avoided when taking prescription drugs. However, please consult your doctor as he or she may instruct you to avoid this supplement based on your specific circumstances. Zinc should be used with caution when combined with: - Antibiotics (i.e. tetracycline and fluoroquinolone antibiotics)

Given that no two people are alike, if you are taking any medications you should be aware that potential drug-nutrient interactions may occur and are encouraged to consult a health care professional before using this product. Combining certain prescription drugs and dietary supplements can lead to undesirable effects such as: - Diminished drug effectiveness - Reduced supplement effectiveness

Keep out of the reach of children.

Formulation Notes

Calcium citrate + magnesium with vitamin D 400 IU

Additional Information

Magnesium should be avoided when taking: - Current research does not indicate that this supplement should be avoided when taking prescription drugs

Interactions: Calcium should be avoided when taking: - Current research does not indicate that this supplement should be avoided when taking prescription drugs.

To preserve quality and freshness, keep bottle tightly closed. Store in a cool, dry place.

Metadata

Product Details

DSLD Entry Date2017-02-24
Product TypeMulti-Vitamin and Mineral (MVM)
FormTablet or Pill
DSLD ID71384
Data Updated2026-04-11
Research

Research Evidence

511
Research Sources
57
Avg Quality
266
Meta Analysis
95
Systematic Review
76
Rct
49
Clinical Trial
12
Guideline
4
Regulatory Source
2
Cochrane Review
2
Other
2
Narrative Review
1
Openfda Safety
A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
A First-line drugs for hypertension
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
A Beta-blockers for hypertension
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.