Cognitex With Brain Shield by Life Extension — Ingredients, Evidence & Safety

Product Label

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Safety Alerts

ℹ️ Contains proprietary blend — exact ingredient amounts not disclosed

Label Data

3 Softgel(s) Serving Size

30 Servings

Other Combinations Product Type

33% Evidence Coverage

Supplement Facts — Evidence Check

Alpha-Glyceryl Phosphoryl Choline

600 mg

✅ 1.1× RDA — within safe limits 📚 36 studies (Tier A: 1, B: 7)

RDA 550mg This product: 600mg UL 3500mg

Phosphatidylserine

100 mg

📊 Market median: 100.0mg (108 products)

Median 100.0mg This product: 100mg

Brain Shield

50 mg

Vinpocetine

20 mg

Leucoselect Grape extract

150 mg

BlueActiv Wild Blueberry extract

150 mg

Sensoril Ashwagandha extract

125 mg

📊 Market median: 450.0mg (502 products) 📚 28 studies (Tier A: 0, B: 8)

This product: 125mg

Uridine-5'-Monophosphate

50 mg

✅ Within RDA (0.1× RDA of 700 mg) 📚 12 studies (Tier A: 0, B: 3)

RDA 700mg This product: 50mg UL 4000mg

Proprietary NeuroProtection Complex Blend

125 mg

Other Ingredients

Safflower Oil Gelatin Glycerin Sunflower Lecithin purified Water Sorbitol Maltodextrin Carob color Silica modified Food Starch

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (97% of products) Structure/Function (90% of products) Nutrient (42% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Read the entire label and follow the directions carefully prior to use. DIRECTIONS: Take three (3) softgels in the morning with or without food, or as recommended by a healthcare practitioner.

⚠️ Warnings & Precautions

CAUTION: If you are taking anti-coagulant or anti-platelet medications, or have a bleeding disorder, consult your healthcare provider before taking this product.

WARNINGS: ~ KEEP OUT OF REACH OF CHILDREN.

~ DO NOT EXCEED RECOMMENDED DOSE. ~ Do not purchase if outer seal is broken or damaged.

~ When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

🧪 Formulation Notes

(Gastrodin)

Non-GMO

Additional Information

Scan for product info

Store tightly closed in a cool, dry place.

Enhances Cognitive Function*

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

Sharp-PS Green

Product Details

UPC / SKU 7 37870 18969 5

DSLD Entry Date 2016-05-22

Product Type Other Combinations

Form Softgel Capsule

Brand Life Extension

DSLD ID 59786

Data Updated 2026-04-11

Research Evidence

28 Research Sources

47 Avg Quality Score

11 Clinical Trial

8 Rct

2 Guideline

2 Meta Analysis

2 Regulatory Source

1 Systematic Review

1 Openfda Safety

B Greater Choline-Containing Compounds and Myo-inositol in Treatment-Resistant Versus Responsive Schizophrenia: A 1H-Magnetic Resonance Spectroscopy Meta-analysis

Meta Analysis Biological psychiatry. Cognitive neuroscience and neuroimaging 2024

PubMed DOI

B Integrating multi-structure covalent docking with machine-learning consensus scoring enhances potency ranking of human acetylcholinesterase inhibitors.

Guideline Briefings in bioinformatics 2026

PubMed DOI

B Evidence-based clinical practice guidelines for functional dyspepsia 2021.

Guideline Journal of gastroenterology 2022

PubMed DOI

B Scientific Opinion on health claims related to choline

Regulatory Source EFSA Journal 2011

DOI

C Effectiveness of nutritional interventions to prevent nonprogressive congenital and perinatal brain injuries: a systematic review and meta-analysis of randomized trials

Meta Analysis Nutrition reviews 2022

PubMed DOI

C Two methods for assessment of choline status in a randomized crossover study with varying dietary choline intake in people: isotope dilution MS of plasma and in vivo single-voxel magnetic resonance spectroscopy of liver.

Rct The American journal of clinical nutrition

PubMed DOI

C Choline and betaine concentrations in plasma discriminate levels of dietary choline intake in healthy adults: analysis of a double-blind randomized crossover controlled feeding study.

Rct The American journal of clinical nutrition

PubMed DOI

C Nutrient-based therapies for bipolar disorder: a systematic review

Systematic Review Psychotherapy and psychosomatics 2013

PubMed DOI

C The association of betaine, homocysteine and related metabolites with cognitive function in Dutch elderly people

Rct The British journal of nutrition 2007

PubMed

C Differential metabolism of choline supplements in adult volunteers.

Rct European journal of nutrition

PubMed DOI

View all evidence for Choline →