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EstroPause

product on market Softgel Capsule Irwin Naturals Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 40% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Calcium and magnesium support bone health, while soy isoflavones and St. John’s Wort are used to manage menopausal symptoms with moderate to limited evidence. Fish oil provides omega-3 fatty acids for general wellness. Overall evidence coverage for this specific formulation is very low.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for EstroPause
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Liquid Softgel(s)
Serving Size
20
Servings
Other Combinations
Product Type
40%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calcium
500 mg (50% DV)
200 mg (50% DV)
Within RDA (0.5× RDA) 316 studies (A:8, B:159)
2158 mg
Market median: 750.0mg (447 products) 393 studies (A:18, B:204)
St John’s Wort extract
300 mg
Market median: 60.0mg (94 products) 13 studies (A:0, B:7)
Market median: 80.0mg (136 products)
Red Clover powder
40 mg
Market median: 450.0mg (390 products) 160 studies (A:0, B:63)
Chaste Tree extract
20 mg
BioPerine Complex
6 mg

Other Ingredients

Gelatin purified Water Glycerin Soy Lecithin Titanium Dioxide Beeswax Lycopene
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Full Disclosure Ingredient Panel DIRECTIONS: (Adult) Take two (2) to four (4) Liquid Soft- Gels a day with meals. May be taken all at once or divided throughout the day.

Warnings & Precautions

Usage Warning: Do not use if safety seal is broken.

St. John’s Wort may interact with medications.

Avoid excessive sun exposure as use of this product may cause your skin to be extra sensitive to UV sources.

Check with your doctor before using this product if you are using medication or have any medical conditions. Do not use if you may become pregnant, are pregnant or nursing.

Do not exceed recommended daily intake.

Not intended for use by persons under 18. KEEP OUT OF REACH OF CHILDREN.

WARNING: (State of California Prop 65) This product contains a chemical known to the State of California to cause birth defects of other reproductive harm.

Contains: Fish (anchovy, sardine), Soy

Formulation Notes

EstroPause Menopause Support* is formulated specifically for aging women.*

~Minerals: Calcium and Magnesium are two of the most important minerals for pre-menopausal women and support the structure and function of bones, muscles and nerves. ~Botanicals: This multi-approach formula contains women’s health herbs, including Black Cohosh, Chasteberry and Red Clover.* Ginseng has been traditionally used as a tonic to combat physical fatigue and to support cognitive function.*

Calcium ~Magnesium ~Black Cohosh

Contains: Fish (anchovy, sardine), Soy

No preservatives added.

Additional Information

~Female Support*: Menopause is a natural stage of life that all women must go through. To make the transition smooth and easy, many women require additional support.*

What makes us different: Liquid Soft-Gels - The nutrients in these easy-to-swallow Liquid Soft-Gels are released fast. Other forms of delivery can contain binders and fillers that may cause stomach upset and offer no nutritional value. Advanced Liquid Soft- Gels provide an optimum delivery system.

We employ compliance testing to ensure purity and potency

QUALITY GUARANTEED PASS

{Globe} Global Responsibility - Over the years we have donated to organizations that support the environment and the health of our children.

Store in a cool, dry place.

QUESTIONS: Call Consumer Affairs 1-800-297-3273 Weekdays 8:00 AM to 5:00 PM (PST)

3044-LAB-06/15 IN036244 V16

Menopause Support

Promotes Female Health Throughout All Stages of Menopause

To join our Wellness Club and receive tips on how to improve your health, please visit us at www.IrwinNaturals.com/wellness1

Metadata

Product Details

UPC / SKU7 10363 26244 0
DSLD Entry Date2016-04-22
Product TypeOther Combinations
FormSoftgel Capsule
DSLD ID56507
Data Updated2026-04-11
Research

Research Evidence

849
Research Sources
56
Avg Quality
450
Meta Analysis
152
Rct
137
Systematic Review
73
Clinical Trial
11
Regulatory Source
7
Other
7
Guideline
3
Openfda Safety
2
Cochrane Review
2
Observational
A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019 PubMed DOI
A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021 PubMed DOI
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.