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TriFlex Fast-Acting

product on market Tablet or Pill GNC Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 29% of ingredients have research evidence
B Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Glucosamine, chondroitin, and MSM are commonly used to support joint health, though research evidence for their efficacy remains limited and mixed. Vitamin C provides antioxidant support and is essential for collagen synthesis. These ingredients are generally well-tolerated, contributing to a high safety profile for most users.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for TriFlex Fast-Acting
Open Full PDF View on NIH DSLD →
Details

Label Data

4 Yellow Tablet(s)
Serving Size
Other Combinations
Product Type
29%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin C
30 mg (50% DV)
Sodium
130 mg (5% DV)
Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
Market median: 600.0mg (79 products) 25 studies (A:0, B:6)
MSM
250 mg
Market median: 1000.0mg (2 products)
Fast-Acting Proprietary Blend (Herb/Botanical)
250 mg
Market median: 100.0mg (173 products)

Other Ingredients

Cellulose Titanium Dioxide Vegetable Acetoglycerides natural Vanilla flavor Riboflavin Sucralose
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

DIRECTIONS: As a dietary supplement, take the contents of one packet daily with a meal.

To ensure a complete nutritional program, take daily with these GNC products: - Premium GNC Multivitamin - Ultra Probiotic Complex 25 - CoQ-10 - SuperFoods Whole Foods Blend

Warnings & Precautions

CONTAINS Crustaceans (Shrimp).

WARNING: Consult your physician prior to using this product is you are pregnant, nursing, taking medication, or have a medical condition.

Discontinue use two weeks prior to surgery.

KEEP OUT OF THE REACH OF CHILDREN.

Formulation Notes

CONTAINS Crustaceans (Shrimp).

TriFlex(TM) Fast-Acting – This maximum strength, fast-acting comfort formula features the full potency, clinically studied doses of glucosamine and chondroitin joint comfort and flexibility. Glucosamine and chondroitin help preserve joint function and rebuild cartilage. It combines two important structural components of joint cartilage, MSM and hyaluronic acid (HA), which helps with cushioning joints and maintains the elastic integrity of skin. It also includes 30 mg of vitamin C. Vitamin C is involved in the synthesis of collagen.

No Sugar, No Artificial Colors, No Preservatives, No Wheat, No Gluten, No Dairy, Yeast Free.

- Comprehensive Vitapak(R) program that supports improved join health with TriFlex(TM) Fast-Acting, Triple Strength Fish Oil, White Willow Bark and MSM

Additional Information

GNC Quality Commitment For more than 75 years, GNC has been the leader in the development and manufacture of dietary supplements and is committed to producing the most superior products. We use only the highest quality ingredients manufactured under the strictest quality controls. Every raw material used is tested to ensure its purity and potency. Each product is dated and then shipped immediately to our stores to ensure that you are purchasing the freshest supplements available. GNC Guarantee If you are not 100% completely satisfied, return the unused portion of the product with your receipt to a GNC store within 30 days. Our trained sales staff will either refund your purchase price or, if you prefer, assist you in finding a replacement product to help you LIVE WELL.

CODE 281812 DNG

{Tablet} ACTUAL SIZE

Store in a cool, dry place.

- Maximum strength, fast-acting joint comfort - works in days - Rebuilds cartilage and lubricates joints - Supports natural anti-inflammatory response

Metadata

Product Details

DSLD Entry Date2015-04-24
Product TypeOther Combinations
FormTablet or Pill
BrandGNC
DSLD ID44711
Data Updated2026-04-11
Research

Research Evidence

371
Research Sources
54
Avg Quality
148
Meta Analysis
82
Systematic Review
71
Rct
62
Clinical Trial
2
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Other
1
Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024 PubMed DOI
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.