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Fitness Defender

product on market Capsule Health Defender A Nutraceutical Company Safety: 70/100
70/100

Review before taking

  • Niacin: 250mg is 7.1× the Tolerable Upper Intake Level (35mg)
  • Folate: 25000mg is 25000.0× the Tolerable Upper Intake Level (1.0mg)
  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 75% of ingredients have research evidence
D Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Riboflavin, niacin, and folate are B vitamins that support energy metabolism and cellular function, with strong evidence for their general physiological roles. The proprietary blend lacks specific transparency, contributing to limited overall evidence coverage. The formulation maintains a moderate safety profile.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 250mg is 7.1× the Tolerable Upper Intake Level (35mg)

Folate: 25000mg is 25000.0× the Tolerable Upper Intake Level (1.0mg)

Contains proprietary blend — exact ingredient amounts not disclosed

AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This product received a low score because it contains levels of Niacin and Folate that far exceed the recommended upper limits. Additionally, it uses a proprietary blend, meaning the exact amounts of some ingredients are not disclosed.

Label

Product Label

Label for Fitness Defender
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
60
Servings
Botanical with Nutrients
Product Type
75%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

5 mg (384.6% DV)
3.8× RDA — above typical dose 13 studies (A:0, B:1)
250 mg (1562.5% DV)
Exceeds UL by 7.1× (UL: 35 mg) 196 studies (A:5, B:63)
25000 mcg DFE (6250% DV)
Exceeds UL by 25000.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
Proprietary Blend
300 mg

Other Ingredients

Cellulose Rice Flour
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions for use: Start with one serving (1 Capsule) to access your tolerance. As your tolerance increases you may titrate up dosage see chart below. 1-Capsule= Minimum Flushing 2-Capsules=Medium Flushing 3-Capsules=Full Flush

Warnings & Precautions

Warning: Keep out of the reach of children.

Consult with your health care practitioner if you are trying to get or are pregnant, nursing, taking other medications, or have other conditions.

Do not use if the safety seal is broken or missing. Always consult with your health care provider about any new dietary supplement regimen.

Formulation Notes

This product is commonly used by those who want to improve their athletic performance.

Fitness & endurance support Gluten-Free-GMP Certified

Gluten-Free-GMP Certified

Additional Information

Store in a cool, dry place.

Health Defender A Nutraceutical Company

Metadata

Product Details

UPC / SKU1 98715 72097 6
DSLD Entry Date2025-08-22
Product TypeBotanical with Nutrients
FormCapsule
DSLD ID337344
Data Updated2026-04-11
Research

Research Evidence

22
Research Sources
49
Avg Quality
8
Rct
4
Meta Analysis
4
Clinical Trial
3
Systematic Review
1
Cochrane Review
1
Regulatory Source
B Effect of vitamin B2, vitamin C, vitamin D, vitamin E and folic acid in adults with essential hypertension: a systematic review and network meta-analysis
Systematic Review BMJ open 2024 PubMed DOI
B Effect of Vitamin B2 supplementation on migraine prophylaxis: a systematic review and meta-analysis
Meta Analysis Nutritional neuroscience 2022 PubMed DOI
B Supplementary vitamin E, selenium, cysteine and riboflavin for preventing kwashiorkor in preschool children in developing countries
Systematic Review The Cochrane database of systematic reviews 2010 PubMed DOI
B Riboflavin supplements for blood pressure lowering in adults.
Cochrane Review The Cochrane database of systematic reviews PubMed DOI
B Associations of dietary vitamin B1, vitamin B2, vitamin B6, and vitamin B12 with the risk of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2022 PubMed DOI
C Prophylaxis of migraine headaches with riboflavin: A systematic review
Systematic Review Journal of clinical pharmacy and therapeutics 2017 PubMed DOI
C Medium-dose riboflavin as a prophylactic agent in children with migraine: a preliminary placebo-controlled, randomised, double-blind, cross-over trial
Rct Cephalalgia : an international journal of headache 2010 PubMed DOI
C The efficacy of 2 different phakic intraocular lens implant in keratoconus as an isolated procedure or combined with collagen crosslinking and intra-stromal corneal ring segments: a systematic review and meta-analysis
Meta Analysis International ophthalmology 2023 PubMed DOI
C Epithelium-off photochemical corneal collagen cross-linkage using riboflavin and ultraviolet a for keratoconus and keratectasia: a systematic review and meta-analysis
Meta Analysis The ocular surface 2014 PubMed DOI
C Improvement of migraine symptoms with a proprietary supplement containing riboflavin, magnesium and Q10: a randomized, placebo-controlled, double-blind, multicenter trial
Rct The journal of headache and pain 2015 PubMed DOI
View all evidence for Riboflavin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.