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Osteo 4000 Calcium

product on market Capsule chiropractor's blend Safety: 96/100
96/100

This product looks safe

  • Magnesium: 450mg is 1.3× the Tolerable Upper Intake Level (350mg)
  • 60% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

This formula combines calcium and phosphorus with microcrystalline hydroxyapatite to support bone mineral density. Vitamin D3 and Vitamin C provide moderate evidence for enhancing calcium absorption and collagen synthesis. Overall, the ingredient profile is supported by established research for skeletal health.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Magnesium: 450mg is 1.3× the Tolerable Upper Intake Level (350mg)

Label

Product Label

Label for Osteo 4000 Calcium
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
30
Servings
Multi-Vitamin and Mineral (MVM)
Product Type
60%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Microcrystalline Hydroxyapatite
4000 mg
Calcium
1000 mg (100% DV)
500 mg (50% DV)
Within RDA (0.7× RDA) 13 studies (A:0, B:3)
Vitamin C
72 mg (120% DV)
1200 IU (300% DV)
2.0× RDA — within safe limits 608 studies (A:16, B:251)
450 mg (113% DV)
Exceeds UL by 1.3× (UL: 350 mg) 316 studies (A:8, B:159)
18 mg (120% DV)
1.6× RDA — within safe limits 263 studies (A:6, B:134)
60 mcg (75% DV)
Within RDA (0.5× RDA) 275 studies (A:9, B:175)
60 mcg (75% DV)
Within RDA (0.5× RDA) 275 studies (A:9, B:175)
2 mg
Market median: 3.0mg (58 products) 3 studies — no high-quality reviews

Other Ingredients

Hypromellose Rice Flour
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested usage: Take 2 capsules up to 3 times daily with a meal or as directed by your qualified healthcare provider.

Warnings & Precautions

Warning: Pregnant or lactating women, diabetics, hypoglycemics and people with known medical conditions and/or taking drugs should consult with a licensed physician and/or pharmacist prior to taking dietary supplements.

Note: Higher dosages of magnesium may produce loose stools.

Formulation Notes

New & enhanced Let's help keep your bones strong!

Optimal calcium Utilize the power of MCHC for your maximum bone health!

Gluten-free

Calcium/Bone Optimal calcium Optimal MCHC Vitamin K1 & K2

Calcium/Bone Bone strength formula Maximum bone density support New & enhanced

Contains: No common allergens.

Gluten free - Dairy free

Additional Information

GMP Quality Guaranteed

Metadata

Product Details

DSLD Entry Date2025-09-25
Product TypeMulti-Vitamin and Mineral (MVM)
FormCapsule
DSLD ID334594
Data Updated2026-04-11
Research

Research Evidence

849
Research Sources
56
Avg Quality
450
Meta Analysis
152
Rct
137
Systematic Review
73
Clinical Trial
11
Regulatory Source
7
Other
7
Guideline
3
Openfda Safety
2
Cochrane Review
2
Observational
A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019 PubMed DOI
A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021 PubMed DOI
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.