🟡 74/100

Review before taking

  • Niacin: 125mg is 3.6× the Tolerable Upper Intake Level (35mg)
  • Folate: 9770mg is 9770.0× the Tolerable Upper Intake Level (1.0mg)
  • 100% of ingredients have research evidence
D Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 125mg is 3.6× the Tolerable Upper Intake Level (35mg)
⚠️ Folate: 9770mg is 9770.0× the Tolerable Upper Intake Level (1.0mg)

This supplement contains levels of Niacin and Folate that significantly exceed the recommended maximum daily intake limits.

Label Data

1 Capsule(s) Serving Size
66 Servings
Vitamin Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

30 mg (2308% DV)
📊 23.1× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 30mg
125 mg NE (781% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 3.6× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 125mg UL 35mg
9770 mcg DFE (2443% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 9770.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 9770mg UL 1.0mg

Other Ingredients

Hypromellose Rice Flour Ascorbyl Palmitate Silicon Dioxide

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (77% of products) Nutrient (60% of products) Approved Health (5% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Suggested use: Adults take 1 capsule twice daily.

⚠️ Warnings & Precautions

Caution: Keep out of reach of children.

🧪 Formulation Notes

Gluten free Non-GMO

Supports: Vigorous folate support Enhanced vitamin B9 function

Targeted bioactive vitamin B9

Professional grade

Additional Information

Exclusive

GMP Certified

Storage: Keep tightly closed in a cool, dry place. Avoid direct sunlight.

Product Details

UPC / SKU 8 50045 01213 7
DSLD Entry Date 2025-02-23
Product Type Vitamin
Form Capsule
Brand NBX Wellness
DSLD ID 327687
Data Updated 2026-04-11

Research Evidence

363 Research Sources
57 Avg Quality Score
187 Meta Analysis
56 Systematic Review
54 Rct
29 Guideline
26 Clinical Trial
6 Cochrane Review
2 Regulatory Source
1 Other
1 Openfda Safety
A Homocysteine-lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
A Community-based intervention packages for reducing maternal and neonatal morbidity and mortality and improving neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015
A Folate Intake and Risk of Pancreatic Cancer: A Systematic Review and Updated Meta-Analysis of Epidemiological Studies
Meta Analysis Digestive diseases and sciences 2021
A The Association Between the Risk of Hypertensive Disorders of Pregnancy and Folic Acid: A Systematic Review and Meta-Analysis
Meta Analysis Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 2021
A A Comparative Study Evaluating the Effectiveness of Folate-Based B Vitamin Intervention on Cognitive Function of Older Adults under Mandatory Folic Acid Fortification Policy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis Nutrients 2024
A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019
A Beneficial effects of folic acid supplementation on lipid markers in adults: A GRADE-assessed systematic review and dose-response meta-analysis of data from 21,787 participants in 34 randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2022
A Folic acid supplementation and blood pressure: a GRADE-assessed systematic review and dose-response meta-analysis of 41,633 participants
Meta Analysis Critical reviews in food science and nutrition 2023
A Digital tracking, provider decision support systems, and targeted client communication via mobile devices to improve primary health care
Meta Analysis The Cochrane database of systematic reviews 2025
View all evidence for Folate →

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