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HydroxyCal

product on market Capsule Karuna Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 40% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Calcium, phosphorus, and vitamin D3 are supported by strong evidence for maintaining bone density and mineral absorption. Vitamin K1 and vitamin C provide additional support for bone matrix mineralization and connective tissue health. Overall evidence coverage for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for HydroxyCal
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
60
Servings
Botanical with Nutrients
Product Type
40%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin C
150 mg (167% DV)
25 mcg (125% DV)
1.7× RDA — within safe limits 608 studies (A:16, B:251)
330 mcg (275% DV)
2.8× RDA — within safe limits 275 studies (A:9, B:175)
Calcium
272 mg (21% DV)
80 mg (6% DV)
Within RDA (0.1× RDA) 13 studies (A:0, B:3)
136 mg (32% DV)
Within RDA (0.3× RDA) 316 studies (A:8, B:159)
1 mg (43% DV)
Within RDA (0.4× RDA) 9 studies — no high-quality reviews
Microcrystalline Hydroxyapatite Complex
800 mg
Horsetail
20 mg
1 mg
Market median: 3.0mg (58 products) 3 studies — no high-quality reviews

Other Ingredients

Gelatin Stearate
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Info

Product Information

Directions for Use

Suggested use for adults: Two capsules, three times daily with meals, or as directed by your health care practitioner.

Warnings & Precautions

This product is intended for professional use and is manufactured under strict quality control to ensure the optimum in purity, potency and reliability.

Formulation Notes

Calcium hydroxyapatite complex with Boron

Microcrystalline hydroxyapatite complex (MCHC) is isolated from the freeze-dried bone tissue of BSE-free cattle, and contains calcium, proteins, including collagen, glycosaminoglycans, and growth peptides, along with trace minerals including magnesium, potassium and silicon. Plant silica source providing 20 mg silicon per serving. Manganese is a trademark of Albion Material Boron is a trademark of Albion Material

This product is intended for professional use and is manufactured under strict quality control to ensure the optimum in purity, potency and reliability.

This product contains no yeast, wheat, soy, corn, milk, salt, sugar, artificial coloring, preservatives or flavoring.

Additional Information

Keep in a cool, dry place, tightly capped.

Metadata

Product Details

UPC / SKU0 18647 02106 7
DSLD Entry Date2025-05-21
Product TypeBotanical with Nutrients
FormCapsule
BrandKaruna
DSLD ID327093
Data Updated2026-04-11
Research

Research Evidence

371
Research Sources
54
Avg Quality
148
Meta Analysis
82
Systematic Review
71
Rct
62
Clinical Trial
2
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Other
1
Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024 PubMed DOI
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.