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Circulation & Vein Formula

product on market Capsule SigmaCeutical Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 38% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains ingredients like L-Arginine and Hawthorn extract, which are associated with supporting blood flow and cardiovascular function. Research provides moderate evidence for these components in improving circulation and vein health. The overall evidence coverage for this specific blend remains limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Circulation & Vein Formula
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
90
Servings
Other Combinations
Product Type
38%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

10 mg (50% DV)
Within RDA (0.7× RDA) 196 studies (A:5, B:63)
Market median: 333.0mg (166 products) 9 studies (A:0, B:2)
Market median: 250.0mg (337 products) 127 studies (A:1, B:41)
50 mg
Market median: 500.0mg (143 products)
Butchers Broom root extract
25 mg
Cayenne Pepper fruit, Powder
25 mg
Market median: 285.0mg (90 products) 1 studies — no high-quality reviews
Diosmin
5 mg

Other Ingredients

Gelatin Magnesium Stearate Rice Flour
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested use: 1 capsule taken 1 to 3 times daily preferably with meals or as directed by a healthcare professional.

Warnings & Precautions

Caution: Do not exceed recommended dose. If you are diabetic, or have a known medical condition, consult your physician prior to taking this or any dietary supplement. Notice: Most people should not experience "Niacin skin flush" when using this product. However a few sensitive individuals may experience some flushing. Do not take on an empty stomach.

This product is not intended for pregnant or nursing mothers of children under the age of 18.

This product is not intended for pregnant or nursing mothers of children under the age of 18.

Keep out of the reach of children.

Do not use if safety seal is damaged or missing.

Formulation Notes

World class nutritional supplement formulations

Circulation & Vein Formula with Cayenne & Ginger

Additional Information

Sourced from a GMP Certified Facility Good Manufacturing Practice Quality Assured Formulated in USA

Please go to www.sigmaceutical.com for special discounts & offers! The sum of all health

Store in a cool, dry place.

Metadata

Product Details

UPC / SKUX001QV9IXD
DSLD Entry Date2025-01-23
Product TypeOther Combinations
FormCapsule
BrandSigmaCeutical
DSLD ID321751
Data Updated2026-04-11
Research

Research Evidence

241
Research Sources
55
Avg Quality
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024 PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010 PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010 PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019 PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016 PubMed DOI
View all evidence for Niacin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.