90/100
This product looks safe
- Contains proprietary blend — exact ingredient amounts not disclosed
- 75% of ingredients have research evidence
A
Label Compliance Grade
What the Evidence Says
✨ AI-generated · Qwen 3.6
· methodology
Milk thistle and turmeric extract have moderate evidence for supporting liver function and reducing inflammation. Choline bitartrate is essential for lipid metabolism, though the proprietary blend lacks specific data. Overall, evidence for these combined ingredients is limited due to low coverage.
AI-generated summary based on research evidence. Not medical advice.
Alerts
Safety Alerts
Contains proprietary blend — exact ingredient amounts not disclosed
Details
Label Data
2 Capsule(s)
Serving Size
Other Combinations
Product Type
Ingredients
Supplement Facts — Evidence Check
Market median: 125.0mg (294 products)
38 studies (A:1, B:7)
Market median: 450.0mg (254 products)
243 studies (A:0, B:100)
Market median: 250.0mg (562 products)
55 studies (A:0, B:19)
Other Ingredients
Gelatin
Dicalcium Phosphate
Silica
Magnesium Stearate
Claims
Label Claims — Verification
Unverified
All Other
Unverified
Structure/Function
Info
Product Information
Directions for Use
For adults, take two (2) capsules daily, preferably with meals. As a reminder, discuss the supplements and medications you take with your health care providers.
Warnings & Precautions
Warning: If you are pregnant, nursing or taking any medications, consult your doctor before use.
Discontinue use and consult your doctor if any adverse reactions occur.
Keep out of reach of children.
Tamper resistant: Do not use if imprinted seal under cap is broken or missing.
Formulation Notes
Supports a healthy liver.
Maintain Health
Regulate Physical Function
Additional Information
Store in a dry place and avoid excessive heat.
GMP
Herbal health
Since 1994
Esmondnatural Integrated health
Metadata
Product Details
UPC / SKU6 41399 08637 6
DSLD Entry Date2024-08-22
Product TypeOther Combinations
FormCapsule
Data Updated2026-04-11
Research
Research Evidence
B
Greater Choline-Containing Compounds and Myo-inositol in Treatment-Resistant Versus Responsive Schizophrenia: A 1H-Magnetic Resonance Spectroscopy Meta-analysis
Meta Analysis
Biological psychiatry. Cognitive neuroscience and neuroimaging
2024
PubMed
DOI
B
Integrating multi-structure covalent docking with machine-learning consensus scoring enhances potency ranking of human acetylcholinesterase inhibitors.
Guideline
Briefings in bioinformatics
2026
PubMed
DOI
B
Evidence-based clinical practice guidelines for functional dyspepsia 2021.
Guideline
Journal of gastroenterology
2022
PubMed
DOI
B
Scientific Opinion on health claims related to choline
Regulatory Source
EFSA Journal
2011
DOI
C
Effectiveness of nutritional interventions to prevent nonprogressive congenital and perinatal brain injuries: a systematic review and meta-analysis of randomized trials
Meta Analysis
Nutrition reviews
2022
PubMed
DOI
C
Two methods for assessment of choline status in a randomized crossover study with varying dietary choline intake in people: isotope dilution MS of plasma and in vivo single-voxel magnetic resonance spectroscopy of liver.
Rct
The American journal of clinical nutrition
PubMed
DOI
C
Choline and betaine concentrations in plasma discriminate levels of dietary choline intake in healthy adults: analysis of a double-blind randomized crossover controlled feeding study.
Rct
The American journal of clinical nutrition
PubMed
DOI
C
Nutrient-based therapies for bipolar disorder: a systematic review
Systematic Review
Psychotherapy and psychosomatics
2013
PubMed
DOI
C
The association of betaine, homocysteine and related metabolites with cognitive function in Dutch elderly people
Rct
The British journal of nutrition
2007
PubMed
C
Differential metabolism of choline supplements in adult volunteers.
View all evidence for Choline →
This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.
