🟢 97/100

This product looks safe

  • Niacin: 225mg is 6.4× the Tolerable Upper Intake Level (35mg)
  • 58% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 225mg is 6.4× the Tolerable Upper Intake Level (35mg)

Label Data

1 Tablet(s) Serving Size
30 Servings
Other Combinations Product Type
58% Evidence Coverage

Supplement Facts — Evidence Check

225 mg (1406% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 6.4× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 225mg UL 35mg
45 mg (2647% DV)
📊 34.6× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 45mg UL 100mg
60 mg (1200% DV)
📊 12.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 60mg
Calcium
300 mg (23% DV)
300 mg (71% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 300mg
300 mg
📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)
This product: 300mg
Gamma-Aminobutyric Acid
300 mg
300 mg
📊 Market median: 500.0mg (180 products) 📚 5 studies (Tier A: 0, B: 1)
This product: 300mg
Glycine
225 mg
📊 Market median: 300.0mg (214 products) 📚 23 studies (Tier A: 0, B: 6)
This product: 90mg
📊 Market median: 250.0mg (60 products) 📚 7 studies (Tier A: 0, B: 1)
This product: 90mg
Hops, Powder
45 mg

Other Ingredients

Microcrystalline Cellulose Stearic Acid Stearate Croscarmellose Sodium Silicon Dioxide Hydroxypropyl Methylcellulose Polyethylene Glycol

Label Claims — Verification

All Other
Structure/Function
All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Suggested Use: As a dietary supplement, take 1 to 3 tablets with a meal. At night, take 1 to 3 tablets one half to one hour before bedtime, or as directed by your healthcare practitioner.

⚠️ Warnings & Precautions

Warning: Do not take this product if taking any MAO inhibitors or antidepressants. If pregnant or nursing, consult your healthcare practitioner before taking this product.

Keep out of reach of children.

Contains: Soy.

🧪 Formulation Notes

Color of this product may vary due to color variations of the ingredients.

A Dietary Supplement to support relaxation and normal sleep

Gluten free

Vegetarian

Additional Information

Store in a cool, dry place.

Product Details

UPC / SKU 8 55524 00446 7
DSLD Entry Date 2024-09-25
Product Type Other Combinations
Form Tablet or Pill
DSLD ID 315830
Data Updated 2026-04-11

Research Evidence

241 Research Sources
55 Avg Quality Score
113 Meta Analysis
75 Systematic Review
32 Rct
11 Clinical Trial
3 Other
3 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016
View all evidence for Niacin →

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