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5-HTP Complex

product on market Capsule Orzax Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 80% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

This complex combines 5-HTP and L-Tryptophan, which have moderate evidence for supporting mood regulation via serotonin synthesis. Riboflavin and folic acid act as essential cofactors in these metabolic pathways, while Rhodiola is used to manage stress responses. Overall, clinical evidence for this specific combination of ingredients is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for 5-HTP Complex
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
60
Servings
Botanical with Nutrients
Product Type
80%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

2.8 mg (215% DV)
2.2× RDA — within safe limits 13 studies (A:0, B:1)
400 mcg (100% DV)
Within RDA (1.0× RDA) 226 studies (A:10, B:105)
Market median: 100.0mg (116 products) 18 studies (A:0, B:3)
100 mg
Market median: 500.0mg (70 products)
100 mg
Market median: 300.0mg (122 products) 22 studies (A:0, B:7)

Other Ingredients

Microcrystalline Cellulose Silicon Dioxide Magnesium Stearate Vegetable Capsule
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: As a dietary supplement, take 2 capsules daily, or as recommended by a physician.

Warnings & Precautions

Caution: Keep this product out of the reach of children.

Do not use if damaged or open containers. Do not exceed the recommended dose. Seek medical advice if an undesired effect is observed.

If pregnant, nursing or taking medication, consult your physician before use.

Sealed for security

Formulation Notes

5-HTP an L-tryptophan are crucial for the production of serotonin which is the key neurotransmitter responsible for modulating mood. Rhodiola is an adaptogen, which means it helps the body adapt to stress. Riboflavin and folic acid also help regulate and improve mood. Orzax 5-HTP Complex helps promote positive mood, and supports healthy energy levels.

Dairy free

Halal

100 mg 5-HTP with L-Tryptophan, Rhodiola, Folic Acid, and Vitamin B2

Promotes a positive mood Supports healthy energy levels.

Made in Turkey

Additional Information

Store at room temperature in a dry place.

Halal GMP Good manufacturing practice

Metadata

Product Details

UPC / SKU8 60007 86324 0
DSLD Entry Date2024-04-23
Product TypeBotanical with Nutrients
FormCapsule
BrandOrzax
DSLD ID310477
Data Updated2026-04-11
Research

Research Evidence

21
Research Sources
53
Avg Quality
11
Systematic Review
6
Rct
4
Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018 PubMed DOI
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001 PubMed
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002 PubMed
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025 PubMed DOI
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023 PubMed
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025 PubMed DOI
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010 PubMed
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020 PubMed DOI
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.