Home/ Supplements/ 5 Htp/ 5-HTP 5-Hydroxy-L-Trytophan 50

5-HTP 5-Hydroxy-L-Trytophan 50

product on market Capsule LifeLink Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

5-HTP serves as a precursor to serotonin and is used to support mood and sleep regulation. There is moderate evidence suggesting its efficacy in managing depressive symptoms. However, overall evidence coverage for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for 5-HTP 5-Hydroxy-L-Trytophan 50
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
Amino acid/Protein
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

50 mg
Market median: 100.0mg (116 products) 18 studies (A:0, B:3)

Other Ingredients

Croscarmelose Sodium Magnesium Stearate Gelatin
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

For best results avoid taking Vitamin B6 two (2) hours before or after taking 5-HTP.

Suggested Use: Doses vary according to use. Consult your health care professional.

Warnings & Precautions

For best results avoid taking Vitamin B6 two (2) hours before or after taking 5-HTP.

Formulation Notes

5-Hydroxy-L-Tryptophan 50

Additional Information

5-HTP (5-hydroxy-L-tryptophan) is the immediate precursor of serotonin. Low levels of serotonin are associated with depression, obesity and sleep disorders.

Metadata

Product Details

UPC / SKU6 39793 10103 0
DSLD Entry Date2012-08-24
Product TypeAmino acid/Protein
FormCapsule
DSLD ID11728
Data Updated2026-04-11
Research

Research Evidence

21
Research Sources
53
Avg Quality
11
Systematic Review
6
Rct
4
Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018 PubMed DOI
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001 PubMed
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002 PubMed
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025 PubMed DOI
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023 PubMed
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025 PubMed DOI
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010 PubMed
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020 PubMed DOI
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025 PubMed DOI
View all evidence for 5 Htp →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.