🟢 96/100

This product looks safe

  • Folate: 833mg is 833.0× the Tolerable Upper Intake Level (1.0mg)
  • 89% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

This formula contains B vitamins, folate, and magnesium, which have moderate to strong evidence for supporting neurological function and metabolic processes. Vitamin C provides additional antioxidant support. The ingredient profile is associated with a high safety score, indicating a low risk of adverse effects for most users.

AI-generated summary based on research evidence. Not medical advice.

Product Label

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Safety Alerts

⚠️ Folate: 833mg is 833.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

2 Capsule(s) Serving Size
30 Servings
Other Combinations Product Type
89% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin C
100 mg (111% DV)
20 mg (125% DV)
✅ 1.4× RDA — within safe limits 📚 196 studies (Tier A: 5, B: 63)
RDA 14mg This product: 20mg UL 35mg
6.7 mg (394% DV)
📊 5.2× RDA — above typical dose (UL: 100 mg) 📚 114 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 6.7mg UL 100mg
833 mcg DFE (208% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 833.0× (UL: 1.0 mg) 📚 226 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 833mg UL 1.0mg
100 mg (24% DV)
✅ Within RDA (0.2× RDA of 420 mg) 📚 316 studies (Tier A: 8, B: 159)
RDA 420mg This product: 100mg UL 350mg
10 mg (91% DV)
✅ Within RDA (0.9× RDA of 11 mg) 📚 263 studies (Tier A: 6, B: 134)
RDA 11mg This product: 10mg UL 40mg
📊 Market median: 100.0mg (116 products) 📚 18 studies (Tier A: 0, B: 3)
This product: 100mg
500 mg
📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)
This product: 500mg
200 mg
📊 Market median: 500.0mg (180 products) 📚 5 studies (Tier A: 0, B: 1)
This product: 200mg

Other Ingredients

Cellulose Water

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (54% of products)

Target Groups

Adult (18 - 50 Years) Women (not pregnant or lactating) Gluten Free

Product Information

📋 Directions for Use

Recommendations: As a dietary supplement, take 2 capsules, 1-2 times daily, between meals.

⚠️ Warnings & Precautions

Warning: Not to be taken by pregnant or lactating women. If you have any health conditions or are taking medication, particularly psychiatric medications, consult your healthcare professional before use. Do not use concurrently with antidepressants.

Keep out of the reach of children.

Use only if safety seal is intact.

🧪 Formulation Notes

Certified Gluten-Free by the Gluten-Free Certified Organization www.gluten.org Gluten-Free, Non-GMO & Hypoallergenic

PureSYNAPSE product line; Supports serotonin production to help promote mood, relaxation, and healthy eating behavior Gluten-Free, Non-GMO & Hypoallergenic

Additional Information

Store in a cool, dry place.

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity. Scan to learn about our hypoallergenic supplements

GFCO.org (Gluten-Free Certification Organization)

Product Details

UPC / SKU 7 66298 02408 0
DSLD Entry Date 2023-12-14
Product Type Other Combinations
Form Capsule
DSLD ID 299753
Data Updated 2026-04-11

Research Evidence

371 Research Sources
54 Avg Quality Score
148 Meta Analysis
82 Systematic Review
71 Rct
62 Clinical Trial
2 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Other
1 Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021
View all evidence for Vitamin C →

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DSLD ID: 299753 Fetched: 2026-04-11
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