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+CAL+ with Ipriflavone

product on market Capsule Pure Encapsulations Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 64% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Calcium, magnesium, and vitamin D are supported by strong evidence for maintaining bone density and skeletal health. Zinc and vitamin K provide moderate support for mineral absorption and bone mineralization. The combination targets bone structural integrity, though overall evidence coverage for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for +CAL+ with Ipriflavone
Open Full PDF View on NIH DSLD →
Details

Label Data

3 Capsule(s)
Serving Size
117
Servings
Other Combinations
Product Type
64%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

10.7 mcg (54% DV)
Within RDA (0.7× RDA) 608 studies (A:16, B:251)
184 mcg (153% DV)
1.5× RDA — within safe limits 275 studies (A:9, B:175)
Calcium
400 mg (31% DV)
49 mg (12% DV)
Within RDA (0.1× RDA) 316 studies (A:8, B:159)
12 mg (109% DV)
1.1× RDA — within safe limits 263 studies (A:6, B:134)
1 mg (111% DV)
1.1× RDA — within safe limits 37 studies (A:0, B:11)
2.1 mg (91% DV)
Within RDA (0.9× RDA) 9 studies — no high-quality reviews
30 mcg
Within RDA (0.2× RDA) 275 studies (A:9, B:175)
0.85 mg
Market median: 3.0mg (58 products) 3 studies — no high-quality reviews
Ipriflavone
214 mg
9 mg
Market median: 108.0mg (8 products) 9 studies (A:0, B:4)

Other Ingredients

Cellulose Water Ascorbyl Palmitate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Recommendations: As a dietary supplement, take 3 capsules, 1-2 times daily, with meals.

Warnings & Precautions

Warning: Not to be taken by pregnant or lactating women. Vitamin K may be contraindicated with Coumadin (Warfarin). If you have any health condition or are taking medication, particularly blood thinning medication, consult your health professional before use.

Keep out of the reach of children.

Use only if safety seal is intact.

Formulation Notes

Certified Gluten-Free by the Gluten-Free Certification Organization, www.gluten.org

Comprehensive bone support Gluten-free, Non-GMO & hypoallergenic

Gluten-free, Non-GMO & hypoallergenic

Additional Information

Store in a cool, dry place.

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity. Scan to learn more about our hypoallergenic supplements

GFCO.org (Gluten-Free Certification Organization)

Metadata

Product Details

UPC / SKU7 66298 01532 3
DSLD Entry Date2023-07-18
Product TypeOther Combinations
FormCapsule
BrandPure Encapsulations
DSLD ID294082
Data Updated2026-04-11
Research

Research Evidence

872
Research Sources
53
Avg Quality
309
Meta Analysis
309
Clinical Trial
111
Rct
71
Systematic Review
55
Guideline
4
Cochrane Review
4
Regulatory Source
2
Other
2
Narrative Review
2
Observational
1
Openfda Safety
A Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Vitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older men
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Vitamin D supplementation for prevention of cancer in adults
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Interventions for preventing falls in older people in care facilities and hospitals
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Drugs for preventing lung cancer in healthy people
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A High prevalence of vitamin D deficiency in Asia: A systematic review and meta-analysis
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A The effect of vitamin D supplementation on depressive symptoms in adults: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A Interventions for preventing falls in older people living in the community
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
View all evidence for Vitamin D →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.