🟢 97/100

This product looks safe

  • Folate: 12750mg is 12750.0× the Tolerable Upper Intake Level (1.0mg)
  • 62% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Folate: 12750mg is 12750.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

2 Capsule(s) Serving Size
30 Servings
Other Combinations Product Type
62% Evidence Coverage

Supplement Facts — Evidence Check

6.23 mg (366% DV)
📊 4.8× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 6.23mg UL 100mg
12750 mcg DFE (3188% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 12750.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 12750mg UL 1.0mg
156.8 mcg (6533% DV)
📊 65.3× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.15680000000000002mg
20 mg (5% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 20mg
GABA
350 mg
📊 Market median: 300.0mg (240 products) 📚 11 studies — no high-quality reviews
This product: 200mg
175 mg
📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)
This product: 175mg
175 mg
📊 Market median: 200.0mg (358 products) 📚 9 studies (Tier A: 0, B: 2)
This product: 175mg
📊 Market median: 300.0mg (214 products) 📚 23 studies (Tier A: 0, B: 6)
This product: 150mg
Lemon Balm
75 mg
Passion Flower extract
55 mg
📊 Market median: 100.0mg (116 products) 📚 15 studies (Tier A: 0, B: 3)
This product: 30mg
Lithium Orotate
3.8 mg

Other Ingredients

Magnesium Stearate Microcrystalline Cellulose Hypromellose

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (98% of products) Structure/Function (89% of products) Nutrient (43% of products)

Target Groups

Adult (18 - 50 Years) Women (not pregnant or lactating)

Product Information

📋 Directions for Use

Suggested use: As a dietary supplement, take two (2) capsules once daily, with at least 8 oz. of water or as directed by a healthcare professional. Do not exceed recommended dosage in 24 hour period.

⚠️ Warnings & Precautions

Keep out of reach of children.

Do not use if safety seal is damaged or missing.

Warning: For adult use only at bedtime.

This product is not to be taken by pregnant or lactating women. If you are taking anti-depressants, birth control pills or other medications, consult with your healthcare professional before using this product.

Discontinue use two weeks prior to surgery. Use of this product may cause your skin to be extra sensitive to uv sources such as artificial or natural sunlight. Avoid excessive exposure from these sources.

Do not exceed recommended dosage in 24 hour period.

🧪 Formulation Notes

Product has been manufactured at a cGMP facility.

Supports restful sleep

Time released with B12 to wake up refreshed

Additional Information

Store in a cool, dry place.

30-day supply

Product Details

UPC / SKU 8 50002 95650 4
DSLD Entry Date 2022-08-23
Product Type Other Combinations
Form Capsule
DSLD ID 272256
Data Updated 2026-04-11

Research Evidence

153 Research Sources
55 Avg Quality Score
71 Systematic Review
51 Meta Analysis
19 Rct
6 Clinical Trial
2 Other
2 Regulatory Source
1 Openfda Safety
A Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ (Clinical research ed.) 2013
A Homocysteine lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2009
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019
A Exploring the causal associations of micronutrients on urate levels and the risk of gout: A Mendelian randomization study
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024
A Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015
B Prophylactic drug management for febrile seizures in children
Meta Analysis The Cochrane database of systematic reviews 2021
B Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review
Systematic Review JAMA 2016
B The potential role of nutritional components in improving brain function among patients with Alzheimers disease: a meta-analysis of RCT studies
Meta Analysis Neurosciences (Riyadh, Saudi Arabia) 2020
B Pyridoxine (vitamin B6) supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2006
B Effect of ginger in the treatment of nausea and vomiting compared with vitamin B6 and placebo during pregnancy: a meta-analysis
Meta Analysis The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022
View all evidence for Vitamin B6 →

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