🟢 86/100

This product is generally safe

  • Niacin: 40mg is 1.1× the Tolerable Upper Intake Level (35mg)
  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 60% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 40mg is 1.1× the Tolerable Upper Intake Level (35mg)
ℹ️ Contains proprietary blend — exact ingredient amounts not disclosed

Label Data

2 Capsule(s) Serving Size
20 Servings
Other Combinations Product Type
60% Evidence Coverage

Supplement Facts — Evidence Check

Calories
5 {Calories}
Cholesterol
5 mg (2% DV)
0.9 mg (60% DV)
✅ Within RDA (0.8× RDA of 1.2 mg) 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 0.9mg
0.9 mg (50% DV)
✅ Within RDA (0.7× RDA of 1.3 mg) 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 0.9mg
40 mg (200% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.1× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 40mg UL 35mg
8.9 mg (450% DV)
📊 6.8× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 8.9mg UL 100mg
Iron
8.9 mg (50% DV)
17.7 mg (120% DV)
✅ 1.6× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 17.7mg UL 40mg
0.3 mg (20% DV)
✅ Within RDA (0.3× RDA of 0.9 mg) 📚 36 studies (Tier A: 0, B: 11)
RDA 0.9mg This product: 0.3mg UL 10mg
Proprietary Blend
585 mg

Other Ingredients

Gelatin Zinc Liver Chelate iron liver chelate Niacinamide Water Pyridoxine Hydrochloride Copper liver Chelate Calcium Stearate colors Cocarboxylase Riboflavin

Label Claims — Verification

All Other
All Other (99% of products) Structure/Function (83% of products) Nutrient (47% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Suggested Use: Two capsules per day, or as directed.

⚠️ Warnings & Precautions

Caution: This product is processed in a facility that manufactures other products containing soy, milk, egg, wheat, peanut, tree nuts, fish, and shellfish.

Warning: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of reach of children. In case of accidental overdose, call a doctor or poison control center immediately.

Additional Information

5850 16

Sold Through Health Care Professionals

Made in the USA

Whole Food Supplements Since 1929

Product Details

UPC / SKU 8 12122 01135 5
DSLD Entry Date 2013-10-25
Product Type Other Combinations
Form Capsule
DSLD ID 26934
Data Updated 2026-04-11

Research Evidence

100 Research Sources
56 Avg Quality Score
48 Systematic Review
30 Meta Analysis
13 Rct
6 Clinical Trial
1 Cochrane Review
1 Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004
View all evidence for Thiamine →

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