🟢 97/100

This product looks safe

  • Vanadyl Sulfate: 10mg is 5.6× the Tolerable Upper Intake Level (1.8mg)
  • 38% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Vanadyl Sulfate: 10mg is 5.6× the Tolerable Upper Intake Level (1.8mg)

Label Data

2 Tablet(s) Serving Size
30 Servings
Other Combinations Product Type
38% Evidence Coverage

Supplement Facts — Evidence Check

5 mg (294% DV)
📊 3.8× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 5mg UL 100mg
15 mg (136% DV)
✅ 1.4× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 15mg UL 40mg
200 mcg (571% DV)
📊 5.7× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 0.2mg
Cinnamon bark extract
350 mg
📊 Market median: 200.0mg (198 products) 📚 6 studies — no high-quality reviews
This product: 200mg
Indian Kino tree heartwood & bark extract
200 mg
Gymnema leaf extract
200 mg
Prickly Pear
100 mg
📊 Market median: 500.0mg (193 products) 📚 7 studies — no high-quality reviews
This product: 100mg
Bitter Melon Fruit Extract
100 mg
Blueberry
100 mg
📊 Market median: 500.0mg (861 products) 📚 60 studies (Tier A: 4, B: 13)
This product: 10mg
⚠️ Exceeds Tolerable Upper Intake Level by 5.6× (UL: 1.8 mg) 📚 1 studies (Tier A: 0, B: 1)
This product: 10mg UL 1.8mg

Other Ingredients

Cellulose Maltodextrin Croscarmellose Sodium Magnesium Carbonate Silica Magnesium Stearate Stearic Acid

Label Claims — Verification

All Other
Structure/Function
All Other (98% of products) Structure/Function (87% of products) Nutrient (16% of products)

Target Groups

Adult (18 - 50 Years) Women (not pregnant or lactating)

Product Information

📋 Directions for Use

2 daily

Directions: Use only as directed. Take 2 tablets daily with meals.

⚠️ Warnings & Precautions

Warning: Do not use if safety seal is broken or missing.

Keep out of reach of children.

Keep your licensed health care practitioner informed when using this product.

Do not use if you are pregnant.

California residents only Warning: Reproductive harm - www.P65Warnings.ca.gov

🧪 Formulation Notes

Blood glucose support with cinnamon and alpha lipoic acid

Discussion: Blood Sugar Defense is intended to provide nutritive support for normal, healthy blood glucose levels.

Building upon synergistic ingredients, Cinnamon is added for its potential role in providing nutritive support for healthy blood glucose levels.

Clinical Lifestyles formulas are based on the observation and research of healthcare practitioners and scientists.

Additional Information

KAL Innovative quality since 1932

Clincal lifestyles

Store in a cool, dry place.

ActivTab technology guarantees tablet disintegration within 30 minutes according to USP standards.

Product Details

UPC / SKU 0 21245 67204 3
DSLD Entry Date 2021-09-24
Product Type Other Combinations
Form Tablet or Pill
Brand KAL
DSLD ID 254629
Data Updated 2026-04-11

Research Evidence

21 Research Sources
52 Avg Quality Score
13 Rct
4 Meta Analysis
2 Systematic Review
2 Clinical Trial
A Alpha-lipoic acid for diabetic peripheral neuropathy
Systematic Review The Cochrane database of systematic reviews 2024
B Efficacy and Safety of the Combination of Palmitoylethanolamide, Superoxide Dismutase, Alpha Lipoic Acid, Vitamins B12, B1, B6, E, Mg, Zn and Nicotinamide for 6 Months in People with Diabetic Neuropathy
Rct Nutrients 2024
B Alpha Lipoic Acid Supplementation and Iron Homeostasis: A Comprehensive Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials
Meta Analysis International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 2024
B Effectiveness of alpha-lipoic acid in patients with neuropathic pain associated with type I and type II diabetes mellitus: A systematic review and meta-analysis
Meta Analysis Medicine 2023
C The effects of alpha-lipoic acid supplementation on glucose control and lipid profiles among patients with metabolic diseases: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Metabolism: clinical and experimental 2018
C A systematic review and meta-analysis of α-lipoic acid in the treatment of diabetic peripheral neuropathy
Meta Analysis European journal of endocrinology 2012
C Oral Alpha Lipoic Acid Treatment for Symptomatic Diabetic Peripheral Neuropathy: A Randomized Double-Blinded Placebo-Controlled Study
Rct Endocrine, metabolic & immune disorders drug targets 2020
C A randomized, double-blind, placebo controlled study to evaluate the effect of alpha-lipoic acid on inhibition of ADP-and collagen-induced platelet aggregation ex vivo in diabetic neuropathy patients on gabapentin or pregabalin
Rct Journal of postgraduate medicine 2024
C Ranking Alpha Lipoic Acid and Gamma Linolenic Acid in Terms of Efficacy and Safety in the Management of Adults With Diabetic Peripheral Neuropathy: A Systematic Review and Network Meta-analysis
Systematic Review Canadian journal of diabetes 2024
C Effect analysis of tanshinone IIA sulfonate sodium combined with a-lipoic acid in patients with diabetes peripheral neuropathy.
Rct Pakistan journal of pharmaceutical sciences
View all evidence for Alpha Lipoic Acid →

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