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Blood Sugar Defense

product on market Tablet or Pill KAL Safety: 97/100
97/100

This product looks safe

  • Vanadyl Sulfate: 10mg is 5.6× the Tolerable Upper Intake Level (1.8mg)
  • 38% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Chromium, cinnamon bark, and alpha lipoic acid are supported by moderate evidence for helping maintain healthy blood glucose levels. Vitamin B-6 and zinc contribute to overall metabolic function, though the evidence coverage for this specific combination is limited. The profile maintains a high safety score with no significant concerns noted.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Vanadyl Sulfate: 10mg is 5.6× the Tolerable Upper Intake Level (1.8mg)

Label

Product Label

Label for Blood Sugar Defense
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Tablet(s)
Serving Size
30
Servings
Other Combinations
Product Type
38%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

5 mg (294% DV)
3.8× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
15 mg (136% DV)
1.4× RDA — within safe limits 263 studies (A:6, B:134)
200 mcg (571% DV)
5.7× RDA — above typical dose 199 studies (A:1, B:55)
Cinnamon bark extract
350 mg
Market median: 200.0mg (198 products) 6 studies — no high-quality reviews
Indian Kino tree heartwood & bark extract
200 mg
Gymnema leaf extract
200 mg
Prickly Pear
100 mg
Market median: 500.0mg (193 products) 7 studies — no high-quality reviews
Bitter Melon Fruit Extract
100 mg
Blueberry
100 mg
Market median: 500.0mg (861 products) 61 studies (A:4, B:13)
Exceeds UL by 5.6× (UL: 1.8 mg) 1 studies (A:0, B:1)

Other Ingredients

Cellulose Maltodextrin Croscarmellose Sodium Magnesium Carbonate Silica Magnesium Stearate Stearic Acid
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

2 daily

Directions: Use only as directed. Take 2 tablets daily with meals.

Warnings & Precautions

Warning: Do not use if safety seal is broken or missing.

Keep out of reach of children.

Keep your licensed health care practitioner informed when using this product.

Do not use if you are pregnant.

California residents only Warning: Reproductive harm - www.P65Warnings.ca.gov

Formulation Notes

Blood glucose support with cinnamon and alpha lipoic acid

Discussion: Blood Sugar Defense is intended to provide nutritive support for normal, healthy blood glucose levels.

Building upon synergistic ingredients, Cinnamon is added for its potential role in providing nutritive support for healthy blood glucose levels.

Clinical Lifestyles formulas are based on the observation and research of healthcare practitioners and scientists.

Additional Information

KAL Innovative quality since 1932

Clincal lifestyles

Store in a cool, dry place.

ActivTab technology guarantees tablet disintegration within 30 minutes according to USP standards.

Metadata

Product Details

UPC / SKU0 21245 67204 3
DSLD Entry Date2021-09-24
Product TypeOther Combinations
FormTablet or Pill
BrandKAL
DSLD ID254629
Data Updated2026-04-11
Research

Research Evidence

21
Research Sources
52
Avg Quality
13
Rct
4
Meta Analysis
2
Systematic Review
2
Clinical Trial
A Alpha-lipoic acid for diabetic peripheral neuropathy
Systematic Review The Cochrane database of systematic reviews 2024 PubMed DOI
B Efficacy and Safety of the Combination of Palmitoylethanolamide, Superoxide Dismutase, Alpha Lipoic Acid, Vitamins B12, B1, B6, E, Mg, Zn and Nicotinamide for 6 Months in People with Diabetic Neuropathy
Rct Nutrients 2024 PubMed DOI
B Alpha Lipoic Acid Supplementation and Iron Homeostasis: A Comprehensive Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials
Meta Analysis International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 2024 PubMed DOI
B Effectiveness of alpha-lipoic acid in patients with neuropathic pain associated with type I and type II diabetes mellitus: A systematic review and meta-analysis
Meta Analysis Medicine 2023 PubMed DOI
C The effects of alpha-lipoic acid supplementation on glucose control and lipid profiles among patients with metabolic diseases: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Metabolism: clinical and experimental 2018 PubMed DOI
C A systematic review and meta-analysis of α-lipoic acid in the treatment of diabetic peripheral neuropathy
Meta Analysis European journal of endocrinology 2012 PubMed DOI
C Oral Alpha Lipoic Acid Treatment for Symptomatic Diabetic Peripheral Neuropathy: A Randomized Double-Blinded Placebo-Controlled Study
Rct Endocrine, metabolic & immune disorders drug targets 2020 PubMed DOI
C A randomized, double-blind, placebo controlled study to evaluate the effect of alpha-lipoic acid on inhibition of ADP-and collagen-induced platelet aggregation ex vivo in diabetic neuropathy patients on gabapentin or pregabalin
Rct Journal of postgraduate medicine 2024 PubMed DOI
C Ranking Alpha Lipoic Acid and Gamma Linolenic Acid in Terms of Efficacy and Safety in the Management of Adults With Diabetic Peripheral Neuropathy: A Systematic Review and Network Meta-analysis
Systematic Review Canadian journal of diabetes 2024 PubMed DOI
C Effect analysis of tanshinone IIA sulfonate sodium combined with a-lipoic acid in patients with diabetes peripheral neuropathy.
Rct Pakistan journal of pharmaceutical sciences PubMed
View all evidence for Alpha Lipoic Acid →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.