🟢 80/100

This product is generally safe

  • Niacin: 66mg is 1.9× the Tolerable Upper Intake Level (35mg)
  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 25% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 66mg is 1.9× the Tolerable Upper Intake Level (35mg)
ℹ️ Contains proprietary blend — exact ingredient amounts not disclosed

Label Data

1 Vegetarian Capsule(s) Serving Size
30 Servings
Botanical with Nutrients Product Type
25% Evidence Coverage

Supplement Facts — Evidence Check

66 mg (330% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.9× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 66mg UL 35mg
📊 Market median: 500.0mg (70 products)
Median 500.0mg This product: 1000mg
250 mg
📊 Market median: 500.0mg (159 products)
Median 500.0mg This product: 250mg
Proprietary TryptoPure Plus Blend (Herb/Botanical)
285 mg

Other Ingredients

Vegetable Cellulose Magnesium Stearate Maltodextrin Rice Flour modified Food Starch Silica

Label Claims — Verification

All Other
Structure/Function
All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Vegetarian Adult (18 - 50 Years)

Product Information

📋 Directions for Use

DIRECTIONS: Take 2-3 capsules all at once before bedtime, or one capsule on an empty stomach before each meal, or as recommended by a healthcare practitioner. For maximum absorption take with a small amount of carbohydrate, such as diluted juice.

Take separately from food or supplements containing protein or amino acids, especially arginine.

⚠️ Warnings & Precautions

WARNINGS: - KEEP OUT OF REACH OF CHILDREN.

Contains corn and rice.

- DO NOT EXCEED RECOMMENDED DOSE.

- Do not purchase if outer seal is broken or damaged.

- When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition.

CAUTION: Serotonin syndrome is characterized by high levels of serotonin and symptoms like confusion, sweating, agitation, nausea, involuntary muscle contractions, and racing heartbeat. Do not take L-tryptophan if you experience these symptoms. Do not take L-tryptophan in combination with other agents that increase serotonin levels in the central nervous system. Agents that increase serotonin levels can include psychiatric medications (e.g. antidepressants, lithium), migraine medications (e.g. sumatriptan), Parkinson’s disease medications (e.g. carbidopa), and dextromethorphan, an over-the-counter cough suppressant. Do not use before driving or operating heavy machinery.

🧪 Formulation Notes

This product contains NO milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), soybeans, tree nuts, wheat, yeast, or gluten. Contains NO sugar, and no artificial sweeteners, flavors, colors, or preservatives

Additional Information

Store tightly closed in a cool, dry place.

01202A Rev. 10/08

Advanced L-Tryptophan Formula

Natural Sleep Enhancement and Stress Reduction*

Read the entire label and follow the directions carefully prior to use.

AJIPURE(TM) AMINO ACIDS

Product Details

UPC / SKU 7 37870 12029 2
DSLD Entry Date 2011-11-25
Product Type Botanical with Nutrients
Form Capsule
DSLD ID 2511
Data Updated 2026-04-11

Research Evidence

241 Research Sources
55 Avg Quality Score
113 Meta Analysis
75 Systematic Review
32 Rct
11 Clinical Trial
3 Other
3 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016
View all evidence for Niacin →

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