🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

2 Capsule(s) Serving Size
5 Servings
Other Combinations Product Type
50% Evidence Coverage

Supplement Facts — Evidence Check

✅ Within RDA (0.5× RDA of 550 mg) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 300mg UL 3500mg
📊 Market median: 100.0mg (108 products)
Median 100.0mg This product: 100mg

Other Ingredients

Modified Cellulose Dicalcium Phosphate Magnesium Stearate Magnesium Silicate Silicon Dioxide

Label Claims — Verification

All Other
All Other (97% of products) Structure/Function (90% of products) Nutrient (42% of products)

Target Groups

Vegetarian Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Suggested Adult Use: Take 1 capsule twice daily between meals, not later than 4 pm. Intakes up to 6 capsules per day may be beneficial.

⚠️ Warnings & Precautions

Contains soy

🧪 Formulation Notes

Contains soy

Suitable for Vegetarians

Additional Information

CONTAINS NOTHING OTHER THAN LISTED INGREDIENTS

R 12/12

Product Details

UPC / SKU 7 53950 00291 3
DSLD Entry Date 2013-08-23
Product Type Other Combinations
Form Capsule
DSLD ID 24985
Data Updated 2026-04-11

Research Evidence

28 Research Sources
47 Avg Quality Score
11 Clinical Trial
8 Rct
2 Guideline
2 Meta Analysis
2 Regulatory Source
1 Systematic Review
1 Openfda Safety
B Greater Choline-Containing Compounds and Myo-inositol in Treatment-Resistant Versus Responsive Schizophrenia: A 1H-Magnetic Resonance Spectroscopy Meta-analysis
Meta Analysis Biological psychiatry. Cognitive neuroscience and neuroimaging 2024
B Integrating multi-structure covalent docking with machine-learning consensus scoring enhances potency ranking of human acetylcholinesterase inhibitors.
Guideline Briefings in bioinformatics 2026
B Evidence-based clinical practice guidelines for functional dyspepsia 2021.
Guideline Journal of gastroenterology 2022
B Scientific Opinion on health claims related to choline
Regulatory Source EFSA Journal 2011
C Effectiveness of nutritional interventions to prevent nonprogressive congenital and perinatal brain injuries: a systematic review and meta-analysis of randomized trials
Meta Analysis Nutrition reviews 2022
C Two methods for assessment of choline status in a randomized crossover study with varying dietary choline intake in people: isotope dilution MS of plasma and in vivo single-voxel magnetic resonance spectroscopy of liver.
Rct The American journal of clinical nutrition
C Choline and betaine concentrations in plasma discriminate levels of dietary choline intake in healthy adults: analysis of a double-blind randomized crossover controlled feeding study.
Rct The American journal of clinical nutrition
C Nutrient-based therapies for bipolar disorder: a systematic review
Systematic Review Psychotherapy and psychosomatics 2013
C The association of betaine, homocysteine and related metabolites with cognitive function in Dutch elderly people
Rct The British journal of nutrition 2007
C Differential metabolism of choline supplements in adult volunteers.
Rct European journal of nutrition
View all evidence for Choline →

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