Home/ Supplements/ Tryptophan/ 5-HTP L-5-Hydroxy Tryptophan 100 mg

5-HTP L-5-Hydroxy Tryptophan 100 mg

product on market Capsule Vitamin World Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

5-HTP and valerian are supported by moderate evidence for improving sleep and mood. Vitamin B6, magnesium, and niacin serve as cofactors in neurotransmitter synthesis, though the overall evidence coverage for this specific combination is limited. These ingredients are generally recognized as safe at the provided dosages.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for 5-HTP L-5-Hydroxy Tryptophan 100 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
Other Combinations
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

5 mg (25% DV)
Within RDA (0.4× RDA) 196 studies (A:5, B:63)
5 mg (250% DV)
3.8× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
25 mg (6% DV)
Within RDA (0.1× RDA) 316 studies (A:8, B:159)
Market median: 100.0mg (116 products) 18 studies (A:0, B:3)
50 mg
Market median: 300.0mg (214 products) 25 studies (A:0, B:6)

Other Ingredients

Dicalcium Phosphate Gelatin Silica Vegetable Magnesium Stearate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

DIRECTIONS: For adults, take one (1) capsule twice daily as needed or at bedtime as 5-HTP may produce drowsiness.

Warnings & Precautions

Keep out of reach of children.

WARNING: Not intended for use by pregnant or nursing women.

Discontinue use and consult your doctor if any adverse reactions occur.

Do not drive, operate machinery or consume alcohol when taking this product.

Do not use if seal under cap is broken or missing.

If you are taking any medications, consult your doctor before use.

Not intended for use by persons under the age of 18.

Formulation Notes

No Artificial Color, Flavor or Sweetener, No Preservatives, No Sugar, No Milk, No Lactose, No Soy, No Gluten, No Wheat, No Yeast, No Fish. Sodium Free.

Additional Information

Get healthy.

Store in a cool, dry place.

From the moment raw ingredients reach our facilities to the time a finished supplement is packaged, stringent analysis confirms the potency, purity and nutritional content of every nutritional product that bears the Vitamin World name. We guarantee it!

Peak X Free

Pro-Serotonin neurotransmitter

Promotes Calming & Relaxation*

PROD. #5317 B5316 06C

QUALITY ASSURED

Metadata

Product Details

UPC / SKU0 74312 75317 6
DSLD Entry Date2011-11-25
Product TypeOther Combinations
FormCapsule
BrandVitamin World
DSLD ID2465
Data Updated2026-04-11
Research

Research Evidence

29
Research Sources
48
Avg Quality
19
Rct
5
Meta Analysis
3
Systematic Review
2
Clinical Trial
B Prebiotic and probiotic supplementation and the tryptophan-kynurenine pathway: A systematic review and meta analysis
Meta Analysis Neuroscience and biobehavioral reviews 2021 PubMed DOI
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001 PubMed
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002 PubMed
B The impact of tryptophan supplementation on sleep quality: a systematic review, meta-analysis, and meta-regression
Meta Analysis Nutrition reviews 2022 PubMed DOI
B No effects of acute tryptophan depletion on anxiety or mood in weight-recovered female patients with anorexia nervosa
Rct European archives of psychiatry and clinical neuroscience 2023 PubMed DOI
C The association between tryptophan levels and postpartum mood disorders: a systematic review and meta-analysis
Meta Analysis BMC psychiatry 2022 PubMed DOI
C A systematic review of the effect of L-tryptophan supplementation on mood and emotional functioning
Systematic Review Journal of dietary supplements 2021 PubMed DOI
C Comparison between Acupuncture and Nutraceutical Treatment with Migratens® in Patients with Fibromyalgia Syndrome: A Prospective Randomized Clinical Trial.
Rct Nutrients PubMed DOI
C Intake of Lactiplantibacillus plantarum HEAL9 Improves Cognition in Moderately Stressed Subjects: A Randomized Controlled Study.
Rct Nutrients PubMed DOI
C Are tryptophan and 5-hydroxytryptophan effective treatments for depression? A meta-analysis
Meta Analysis The Australian and New Zealand journal of psychiatry 2002 PubMed
View all evidence for Tryptophan →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.