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Hydroxy Tryptophan

product on market Capsule New Sun Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

5-HTP serves as a precursor to serotonin and is researched for its role in supporting mood and sleep. Current evidence for these effects is generally considered moderate. This ingredient profile maintains a high safety score with no significant concerns noted.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Hydroxy Tryptophan
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
60
Servings
Amino acid/Protein
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

50 mg
Market median: 100.0mg (116 products) 18 studies (A:0, B:3)

Other Ingredients

White Rice Flour Gelatin
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Recommendation: As a dietary supplement, take one to four capsules daily in divided doses.

Warnings & Precautions

Do not use if safety seal is broken or missing.

Keep out of reach of children.

Warning: If you are currently taking anti-depressants or MAO inhibiting medications, please consult a physician prior to use.

May cause drowsiness. Do not drive or operate machinery while taking this product.

If pregnant, nursing, taking medications, experiencing health issues, consult your doctor before use.

Formulation Notes

This Product Does Not Contain: Yeast, corn, wheat, egg, sugar, salt, gluten, soy shellfish, or preservatives.

5-HTP

Additional Information

Store in a cool, dry place.

Supplement Facts (continued)

Griffonia simplicifolia is an African plant which is extracted to produce 5-HTP, the intermediate between amino acid and L-tryptophan and serotonin.

Product 50-1 v5.0

Metadata

Product Details

UPC / SKU50-1
DSLD Entry Date2018-01-25
Product TypeAmino acid/Protein
FormCapsule
BrandNew Sun
DSLD ID82469
Data Updated2026-04-11
Research

Research Evidence

29
Research Sources
48
Avg Quality
19
Rct
5
Meta Analysis
3
Systematic Review
2
Clinical Trial
B Prebiotic and probiotic supplementation and the tryptophan-kynurenine pathway: A systematic review and meta analysis
Meta Analysis Neuroscience and biobehavioral reviews 2021 PubMed DOI
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001 PubMed
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002 PubMed
B The impact of tryptophan supplementation on sleep quality: a systematic review, meta-analysis, and meta-regression
Meta Analysis Nutrition reviews 2022 PubMed DOI
B No effects of acute tryptophan depletion on anxiety or mood in weight-recovered female patients with anorexia nervosa
Rct European archives of psychiatry and clinical neuroscience 2023 PubMed DOI
C The association between tryptophan levels and postpartum mood disorders: a systematic review and meta-analysis
Meta Analysis BMC psychiatry 2022 PubMed DOI
C A systematic review of the effect of L-tryptophan supplementation on mood and emotional functioning
Systematic Review Journal of dietary supplements 2021 PubMed DOI
C Comparison between Acupuncture and Nutraceutical Treatment with Migratens® in Patients with Fibromyalgia Syndrome: A Prospective Randomized Clinical Trial.
Rct Nutrients PubMed DOI
C Intake of Lactiplantibacillus plantarum HEAL9 Improves Cognition in Moderately Stressed Subjects: A Randomized Controlled Study.
Rct Nutrients PubMed DOI
C Are tryptophan and 5-hydroxytryptophan effective treatments for depression? A meta-analysis
Meta Analysis The Australian and New Zealand journal of psychiatry 2002 PubMed
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.