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Ultra Relief

product on market Capsule Freeda Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 57% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula combines magnesium, riboflavin, and vitamin B6, which have moderate evidence for supporting migraine prevention. Methylsulfonylmethane and feverfew are included for their anti-inflammatory properties, though clinical evidence for these specific extracts is more limited. The ingredient profile maintains a high safety rating for general use.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Ultra Relief
Open Full PDF View on NIH DSLD →
Details

Label Data

3 Vegetable Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
57%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

225 mg (17308% DV)
173.1× RDA — above typical dose 13 studies (A:0, B:1)
30 mg (1765% DV)
23.1× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
150 mg (36% DV)
Within RDA (0.4× RDA) 316 studies (A:8, B:159)
Market median: 1000.0mg (2 products)
Market median: 380.0mg (120 products) 8 studies — no high-quality reviews
Purple Butterbur root extract
300 mg
Market median: 250.0mg (337 products) 127 studies (A:1, B:41)

Other Ingredients

Vegetable Cellulose Capsule Cellulose Vegetarian Stearate Silica
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

For maximum benefit take daily for 3-4 weeks

Suggested Use: Adults, take three (3) capsules daily preferably with food and liquid.

Warnings & Precautions

Keep out of reach of children.

If you are pregnant, nursing, taking medication, or have a medical condition, consult your health care practitioner prior to using this product.

Formulation Notes

Nutritional support for migraine sufferers

Unique blend of highly researched ingredients

Supports head comfort and relaxation

No Gluten No Lactose No Artificial Colors No Artificial Flavors No Animal Derivatives No Sugar or Starch No Gelatin No Yeast

Vegan

Migraine support

Manufactured in a GMP certified facility Proudly made in the USA Mind Spirit Cognitive

New Square Rabbinical Kashrus Council OU (Kosher)

Ultra Relief w/B2 + Feverfew & Butterbur extracts

Natural color variation may occur in this product.

Additional Information

Next Century Nutrition Freeda The value of innovation since 1928

Vegan

Manufactured in a GMP certified facility

Proudly made in the USA New Square Rabbinical Kashrus Council OU (Kosher)

Store in a cool, dry place. Do not expose to excessive heat or moisture.

Metadata

Product Details

UPC / SKU7 58487 04091 9
DSLD Entry Date2021-04-22
Product TypeOther Combinations
FormCapsule
BrandFreeda
DSLD ID246155
Data Updated2026-04-11
Research

Research Evidence

22
Research Sources
49
Avg Quality
8
Rct
4
Meta Analysis
4
Clinical Trial
3
Systematic Review
1
Cochrane Review
1
Regulatory Source
B Effect of vitamin B2, vitamin C, vitamin D, vitamin E and folic acid in adults with essential hypertension: a systematic review and network meta-analysis
Systematic Review BMJ open 2024 PubMed DOI
B Effect of Vitamin B2 supplementation on migraine prophylaxis: a systematic review and meta-analysis
Meta Analysis Nutritional neuroscience 2022 PubMed DOI
B Supplementary vitamin E, selenium, cysteine and riboflavin for preventing kwashiorkor in preschool children in developing countries
Systematic Review The Cochrane database of systematic reviews 2010 PubMed DOI
B Riboflavin supplements for blood pressure lowering in adults.
Cochrane Review The Cochrane database of systematic reviews PubMed DOI
B Associations of dietary vitamin B1, vitamin B2, vitamin B6, and vitamin B12 with the risk of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2022 PubMed DOI
C Prophylaxis of migraine headaches with riboflavin: A systematic review
Systematic Review Journal of clinical pharmacy and therapeutics 2017 PubMed DOI
C Medium-dose riboflavin as a prophylactic agent in children with migraine: a preliminary placebo-controlled, randomised, double-blind, cross-over trial
Rct Cephalalgia : an international journal of headache 2010 PubMed DOI
C The efficacy of 2 different phakic intraocular lens implant in keratoconus as an isolated procedure or combined with collagen crosslinking and intra-stromal corneal ring segments: a systematic review and meta-analysis
Meta Analysis International ophthalmology 2023 PubMed DOI
C Epithelium-off photochemical corneal collagen cross-linkage using riboflavin and ultraviolet a for keratoconus and keratectasia: a systematic review and meta-analysis
Meta Analysis The ocular surface 2014 PubMed DOI
C Improvement of migraine symptoms with a proprietary supplement containing riboflavin, magnesium and Q10: a randomized, placebo-controlled, double-blind, multicenter trial
Rct The journal of headache and pain 2015 PubMed DOI
View all evidence for Riboflavin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.