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True Calm

product on market Capsule NOW Safety: 95/100
95/100

This product looks safe

  • Niacin: 45mg is 1.3× the Tolerable Upper Intake Level (35mg)
  • 75% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

This formula combines Magnesium, GABA, and Glycine, which have moderate evidence for supporting relaxation and sleep. Niacin and Vitamin B6 contribute to neurological function and neurotransmitter synthesis. Overall evidence coverage for this specific blend is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 45mg is 1.3× the Tolerable Upper Intake Level (35mg)

Label

Product Label

Label for True Calm
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Veg Capsule(s)
Serving Size
Other Combinations
Product Type
75%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

45 mg (281% DV)
Exceeds UL by 1.3× (UL: 35 mg) 196 studies (A:5, B:63)
8 mg (471% DV)
6.2× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
6.5 mg (2% DV)
Market median: 500.0mg (1 products) 316 studies (A:8, B:159)
GABA
200 mg
Glycine
200 mg
200 mg
Market median: 500.0mg (180 products) 5 studies (A:0, B:1)
100 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
25 mg
Market median: 300.0mg (214 products) 25 studies (A:0, B:6)

Other Ingredients

Hypromellose Stearic Acid
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Usage: Take 1 capsule 1 to 3 times daily, preferably on an empty stomach or just before meals.

Warnings & Precautions

Caution: For adults only. May reduce the ability to drive or operate machinery.

Consult physician if pregnant/nursing, taking medication, or have a medical condition.

Keep out of reach of children.

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Formulation Notes

True Calm is a combination of amino acids and their cofactor nutrients formulated to support the normal production and function of calming neurotransmitters in the brain.

True Calm includes GABA and glycine, two amino acids that promote relaxed state of mind, along with Taurine, another amino acid with calming properties. These nutrients are blended with Valerian, which is known to interact with the GABA receptors in the nervous system.

Natural color variation may occur in this product.

Neurotransmitter Support Promotes Relaxed Mood

Amino Acid Blend with B Vitamins & Valerian

Non-GMO

Vegetarian/Vegan

Triangle K (Kosher)

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients.

Additional Information

Triangle K (Kosher)

Amino Acids Family owned since 1968.

GMP Quality Assured

Metadata

Product Details

UPC / SKU7 33739 00155 9
DSLD Entry Date2021-03-25
Product TypeOther Combinations
FormCapsule
BrandNOW
DSLD ID244413
Data Updated2026-04-11
Research

Research Evidence

241
Research Sources
55
Avg Quality
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024 PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010 PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010 PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019 PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016 PubMed DOI
View all evidence for Niacin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.