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Antioxidant & Circulation

product on market Capsule GNC Women's Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 60% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

This formula contains alpha-lipoic acid and resveratrol, which have moderate evidence for supporting antioxidant activity. Turmeric and lutein-zeaxanthin are researched for their roles in inflammatory response and ocular health. Overall, the evidence coverage for this specific ingredient combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Antioxidant & Circulation
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
60%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 200.0mg (198 products) 6 studies — no high-quality reviews
Market median: 450.0mg (254 products) 243 studies (A:0, B:100)
Market median: 167.0mg (311 products) 183 studies (A:0, B:65)
Market median: 10.0mg (105 products) 2 studies (A:0, B:1)
2.2 mg
Market median: 4.0mg (32 products)

Other Ingredients

Gelatin Hydroxypropyl Methylcellulose Microcrystalline Cellulose modified Starch Magnesium Stearate Sucrose Maltodextrin DL-Alpha-Tocopherol Sodium Ascorbate Hydroxypropylcellulose Stearic Acid Silicon Dioxide
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: As a dietary supplement, take contents of one packet daily with food. For maximum benefits, take as directed every day.

Warnings & Precautions

Keep out of reach of children.

Warning: Cancer and reproductive harm - www.p65Warnings.ca.gov.

Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition.

Discontinue use two weeks prior to surgery.

Formulation Notes

Conforms to USP <2091> for weight. Meets USP <2040> for disintegration.

Targeted solutions for head-to-toe support

Includes multivitamin + heart & eye health + brain health + joint health + bone, beauty & hormone formula + antioxidant & circulation + digestive enzymes

Comprehensive support made convenient. With a multivitamin blend clinically proven to make you feel better, plus targeted solutions for head-to-toe support, our Women's Vitapak Program Whole Body has you covered. Heart, Eye & Circulatory Health Features EPA & DHA omega-3s to support heart and eye health and resVida, which is clinically shown to support blood vessel dilation

In a randomized, double-blind, placebo-controlled study of 112 healthy volunteers, subjects taking the GNC vitamin and mineral blends for six weeks experienced significant improvements in serum levels of certain key nutrients compared to a placebo and a basic multivitamin formula based upon multivariate statistical analysis of a group of B-vitamins (thiamin, niacin, riboflavin, pantothenic acid, biotin, folic acid, and vitamins B-6 and B-12) and key antioxidants and cartenoids (a group of beta-carotene, alpha-tocopherol, selenium, lutein, lycopene). Statistical improvements in SF-36 Vitality and Mental Health scores were also observed compared to placebo. In a 12 week multi-center, randomized, double-blind, placebo-controlled study of 60 adults, subjects taking 250mg/day of the joint blend showed a significant 29.8% improvement in joint flexibility and a 19.4% improvement in joint function in 30 days compared to subjects on placebo.

Additional Information

Each Pack Contains: Antioxidant & Circulation

Store in a cool, dry place.

Our quality commitment to you Since 1935, our mission as the industry leader has been to provide you with the highest-quality nutritional supplements. We continue to stand behind this mission. If you are not 100% satisfied with your purchase, return the unused portion of the product with your receipt within 30 days, and we'll either refund your money or find a replacement product that is right for you.

30-Day Supply

Metadata

Product Details

DSLD Entry Date2021-03-25
Product TypeOther Combinations
FormCapsule
DSLD ID243683
Data Updated2026-04-11
Research

Research Evidence

21
Research Sources
52
Avg Quality
13
Rct
4
Meta Analysis
2
Systematic Review
2
Clinical Trial
A Alpha-lipoic acid for diabetic peripheral neuropathy
Systematic Review The Cochrane database of systematic reviews 2024 PubMed DOI
B Efficacy and Safety of the Combination of Palmitoylethanolamide, Superoxide Dismutase, Alpha Lipoic Acid, Vitamins B12, B1, B6, E, Mg, Zn and Nicotinamide for 6 Months in People with Diabetic Neuropathy
Rct Nutrients 2024 PubMed DOI
B Alpha Lipoic Acid Supplementation and Iron Homeostasis: A Comprehensive Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials
Meta Analysis International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 2024 PubMed DOI
B Effectiveness of alpha-lipoic acid in patients with neuropathic pain associated with type I and type II diabetes mellitus: A systematic review and meta-analysis
Meta Analysis Medicine 2023 PubMed DOI
C The effects of alpha-lipoic acid supplementation on glucose control and lipid profiles among patients with metabolic diseases: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Metabolism: clinical and experimental 2018 PubMed DOI
C A systematic review and meta-analysis of α-lipoic acid in the treatment of diabetic peripheral neuropathy
Meta Analysis European journal of endocrinology 2012 PubMed DOI
C Oral Alpha Lipoic Acid Treatment for Symptomatic Diabetic Peripheral Neuropathy: A Randomized Double-Blinded Placebo-Controlled Study
Rct Endocrine, metabolic & immune disorders drug targets 2020 PubMed DOI
C A randomized, double-blind, placebo controlled study to evaluate the effect of alpha-lipoic acid on inhibition of ADP-and collagen-induced platelet aggregation ex vivo in diabetic neuropathy patients on gabapentin or pregabalin
Rct Journal of postgraduate medicine 2024 PubMed DOI
C Ranking Alpha Lipoic Acid and Gamma Linolenic Acid in Terms of Efficacy and Safety in the Management of Adults With Diabetic Peripheral Neuropathy: A Systematic Review and Network Meta-analysis
Systematic Review Canadian journal of diabetes 2024 PubMed DOI
C Effect analysis of tanshinone IIA sulfonate sodium combined with a-lipoic acid in patients with diabetes peripheral neuropathy.
Rct Pakistan journal of pharmaceutical sciences PubMed
View all evidence for Alpha Lipoic Acid →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.