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Circulation & Metabolism Support

product on market Capsule GNC Mega Men Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 67% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Alpha-lipoic acid and L-carnitine are supported by moderate evidence for improving metabolic function and energy utilization. Trans-resveratrol is studied for its role in supporting cardiovascular health and antioxidant activity. Overall, research for these ingredients is well-documented, though evidence coverage for this specific formulation remains limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Circulation & Metabolism Support
Open Full PDF View on NIH DSLD →
Details

Label Data

1 White Capsule(s)
Serving Size
Non-Nutrient/Non-Botanical
Product Type
67%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 200.0mg (198 products) 6 studies — no high-quality reviews
100 mg
Market median: 500.0mg (861 products) 61 studies (A:4, B:13)
Market median: 167.0mg (311 products) 183 studies (A:0, B:65)

Other Ingredients

Cellulose Gelatin Corn Starch Titanium Dioxide
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

To ensure a complete nutritional program, take daily with these GNC products: - Coenzyme Q-10 100 - Turmeric - SuperFoods Whole Foods Blend - TriFlex(TM)

DIRECTIONS: As a dietary supplement, for optimal health benefits take contents of one packet daily with food.

Warnings & Precautions

WARNING: Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition.

Discontinue use two weeks prior to surgery.

KEEP OUT OF REACH OF CHILDREN.

Formulation Notes

No Artificial Colors, No Wheat, No Gluten, No Dairy, Yeast Free.

It also contains nutrients that address the primary health concerns of people with diabetes: blood glucose support, eye health and circulatory health.

Additional Information

"Men who are monitoring their blood sugar levels need extra nutritional support.

{signature} Dr. Frank J. Costa M.D.

PHYSICIAN ENDORSED

Premium ingredients that support glucose metabolism, circulatory health & optimal eye health.

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GNC QUALITY COMMITMENT For more than 77 years, GNC has been the leader in the development of superior nutritional supplements. Our products are produced using only fresh, high-quality ingredients and are manufactured under the strictest quality controls. GNC GUARANTEE If you are not 100% completely satisfied, return the unused portion of the product with your receipt to a GNC store within 30 days. Our trained sales staff will either refund your purchase price or, if you prefer, assist you in finding a replacement product to help you LIVE WELL.

It offers an advanced multivitamin formula plus a nutrition and lifestyle plan that promotes overall health and wellness, as well as key blends of powerful ingredients that support the special health concerns related to diabetes." - Frank J. Costa, M.D.

CODE 344922 KNG

resVida(R)

Circulation & Metabolism Support

ACTUAL SIZE

Also delivers L-carnitine, which facilitates the metabolism of long chain fatty acids, and alpha-lipoic acid, which plays an important role in cellulose energy metabolism.

Metadata

Product Details

DSLD Entry Date2013-11-25
Product TypeNon-Nutrient/Non-Botanical
FormCapsule
DSLD ID27473
Data Updated2026-04-11
Research

Research Evidence

21
Research Sources
52
Avg Quality
13
Rct
4
Meta Analysis
2
Systematic Review
2
Clinical Trial
A Alpha-lipoic acid for diabetic peripheral neuropathy
Systematic Review The Cochrane database of systematic reviews 2024 PubMed DOI
B Efficacy and Safety of the Combination of Palmitoylethanolamide, Superoxide Dismutase, Alpha Lipoic Acid, Vitamins B12, B1, B6, E, Mg, Zn and Nicotinamide for 6 Months in People with Diabetic Neuropathy
Rct Nutrients 2024 PubMed DOI
B Alpha Lipoic Acid Supplementation and Iron Homeostasis: A Comprehensive Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials
Meta Analysis International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 2024 PubMed DOI
B Effectiveness of alpha-lipoic acid in patients with neuropathic pain associated with type I and type II diabetes mellitus: A systematic review and meta-analysis
Meta Analysis Medicine 2023 PubMed DOI
C The effects of alpha-lipoic acid supplementation on glucose control and lipid profiles among patients with metabolic diseases: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Metabolism: clinical and experimental 2018 PubMed DOI
C A systematic review and meta-analysis of α-lipoic acid in the treatment of diabetic peripheral neuropathy
Meta Analysis European journal of endocrinology 2012 PubMed DOI
C Oral Alpha Lipoic Acid Treatment for Symptomatic Diabetic Peripheral Neuropathy: A Randomized Double-Blinded Placebo-Controlled Study
Rct Endocrine, metabolic & immune disorders drug targets 2020 PubMed DOI
C A randomized, double-blind, placebo controlled study to evaluate the effect of alpha-lipoic acid on inhibition of ADP-and collagen-induced platelet aggregation ex vivo in diabetic neuropathy patients on gabapentin or pregabalin
Rct Journal of postgraduate medicine 2024 PubMed DOI
C Ranking Alpha Lipoic Acid and Gamma Linolenic Acid in Terms of Efficacy and Safety in the Management of Adults With Diabetic Peripheral Neuropathy: A Systematic Review and Network Meta-analysis
Systematic Review Canadian journal of diabetes 2024 PubMed DOI
C Effect analysis of tanshinone IIA sulfonate sodium combined with a-lipoic acid in patients with diabetes peripheral neuropathy.
Rct Pakistan journal of pharmaceutical sciences PubMed
View all evidence for Alpha Lipoic Acid →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.