🟢 89/100

This product is generally safe

  • Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • Folate: 666mg is 666.0× the Tolerable Upper Intake Level (1.0mg)
  • 86% of ingredients have research evidence
D Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
⚠️ Folate: 666mg is 666.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

1 Capsule(s) Serving Size
Other Combinations Product Type
86% Evidence Coverage

Supplement Facts — Evidence Check

Total Carbohydrates
1 Gram(s) (1% DV)
50 mg (313% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.4× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 50mg UL 35mg
12.5 mg (735% DV)
📊 9.6× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 12.5mg UL 100mg
666 mcg DFE (167% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 666.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 666mg UL 1.0mg
50 mcg (2083% DV)
📊 20.8× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.05mg
📊 Market median: 1000.0mg (223 products) 📚 11 studies (Tier A: 0, B: 5)
This product: 600mg
30 mg
📊 Market median: 100.0mg (283 products) 📚 142 studies (Tier A: 1, B: 64)
This product: 30mg UL 1200mg

Other Ingredients

plant-derived Capsule Cellulose Magnesium Stearate Silica

Label Claims — Verification

Nutrient
All Other
All Other (99% of products) Structure/Function (74% of products) Nutrient (7% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Women (not pregnant or lactating) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Twice daily vegetarian capsules

Recommendation: Take 1 capsule twice daily, or as recommended by a healthcare professional.

⚠️ Warnings & Precautions

Keep out of reach of children.

Safety sealed with inner seal. Do not use if either is broken or missing.

Warning: Do not use if you are pregnant, may become pregnant or are nursing, or if you have liver disease. If you are taking any medications, consult a healthcare professional before use.

Contains soy.

🧪 Formulation Notes

HeartSure Red Yeast Rice With CoQ10 and B-Complex

Gluten free. No wheat, dairy, artificial colors, flavors or preservatives.

Vegan

Niacin/B6/B12

Premium source

Additional Information

Keep bottle tightly closed.

Quality Global Sourcing Bottled & Tested In the USA

Nature's Way since 1969

Product Details

UPC / SKU 0 33674 15285 0
DSLD Entry Date 2021-02-25
Product Type Other Combinations
Form Capsule
Brand Nature's Way
DSLD ID 243202
Data Updated 2026-04-11

Research Evidence

13 Research Sources
53 Avg Quality Score
5 Rct
5 Meta Analysis
2 Clinical Trial
1 Regulatory Source
B Impact of red yeast rice supplementation on lipid profile: a systematic review and meta-analysis of randomized-controlled trials
Meta Analysis Expert review of clinical pharmacology 2023
B Low Dose Monacolin K Combined with Coenzyme Q10, Grape Seed, and Olive Leaf Extracts Lowers LDL Cholesterol in Patients with Mild Dyslipidemia: A Multicenter, Randomized Controlled Trial
Rct Nutrients 2023
B Original Research: The Effects of Red Yeast Rice Supplementation on Cholesterol Levels in Adults
Meta Analysis The American journal of nursing 2017
B Randomized, Double-Blind, Placebo-Controlled Trial to Test the Effects of a Nutraceutical Combination Monacolin K-Free on the Lipid and Inflammatory Profile of Subjects with Hypercholesterolemia
Rct Nutrients 2022
B Low dose red yeast rice with monacolin K lowers LDL cholesterol and blood pressure in Japanese with mild dyslipidemia: A multicenter, randomized trial
Rct Asia Pacific journal of clinical nutrition 2021
C Impact of Monacolin K-Containing Supplements on Lipid Profile: A Meta-Analysis of Randomised Controlled Trials
Meta Analysis Endocrinology, diabetes & metabolism 2026
C Traditional Chinese lipid-lowering agent red yeast rice results in significant LDL reduction but safety is uncertain - a systematic review and meta-analysis
Meta Analysis Atherosclerosis 2015
C Effects of a nutraceutical combination containing berberine (BRB), policosanol, and red yeast rice (RYR), on lipid profile in hypercholesterolemic patients: A meta-analysis of randomised controlled trials
Meta Analysis Clinica e investigacion en arteriosclerosis : publicacion oficial de la Sociedad Espanola de Arteriosclerosis 2016
C Can red yeast rice and olive extract improve lipid profile and cardiovascular risk in metabolic syndrome?: A double blind, placebo controlled randomized trial
Rct BMC complementary and alternative medicine 2015
C No additional cholesterol-lowering effect observed in the combined treatment of red yeast rice and Lactobacillus casei in hyperlipidemic patients: A double-blind randomized controlled clinical trial
Rct Chinese journal of integrative medicine 2017
View all evidence for Red Yeast Rice →

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