Serotone 5-HTP 100 mg

product on market Capsule Higher Nature 🟢 Safety: 100/100
Brand: Higher Nature
🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

Label for Serotone 5-HTP 100 mg
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Label Data

1 Capsule(s) Serving Size
Other Combinations Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

30 mg NE (188% DV)
✅ 2.1× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 30mg UL 35mg
10 mg (714% DV)
📊 7.7× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 10mg UL 100mg
100 mcg (50% DV)
✅ Within RDA (0.2× RDA of 0.4 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 0.1mg UL 1.0mg
50 mcg (100% DV)
✅ 1.7× RDA — within safe limits 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.05mg
5 mg (50% DV)
✅ Within RDA (0.5× RDA of 11 mg) 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 5mg UL 40mg
100 mg
📊 Market median: 100.0mg (116 products) 📚 15 studies (Tier A: 0, B: 3)
This product: 100mg

Other Ingredients

Rice Bran L-5-Hydroxytryptophan Capsule Vitamin B3 Zinc Citrate Vitamin B6 Vitamin B6 Silicon Dioxide Magnesium Stearate Folic Acid Biotin

Label Claims — Verification

❓ Nutrient
❓ All Other
❓ Structure/Function
All Other (99% of products) Structure/Function (78% of products) Nutrient (52% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Women (not pregnant or lactating) Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

Directions: Take 1 capsule a day preferable before bed with a carbohydrate snack. Do not exceed recommended daily intake.

⚠️ Warnings & Precautions

Storage: Store in a cool, dry place out of reach of children.

Food supplements should not be used as a substitute for a varied and balanced diet and healthy lifestyle.

Warning: Consult your doctor if under medical supervision or taking prescribed medications. Not advisable if pregnant, breastfeeding or if taking antidepressants.

Can cause drowsiness; do not drive or operate machinery if affected.

🧪 Formulation Notes

Free From: Artificial colours, flavourings or preservatives, corn, dairy products, gluten, lactose, maize, salt, soya, sugar, wheat, yeast.

Mind health Advanced formula Optimal benefit

Vegetarian and vegan

Vitamins B3 and B6 contribute to normal psychological function

Additional Information

Storage: Store in a cool, dry place out of reach of children.

This product has not been tested on animals.

Product Details

UPC / SKU 5 031013 100659
DSLD Entry Date 2020-06-24
Product Type Other Combinations
Form Capsule
Brand Higher Nature
DSLD ID 228519
Data Updated 2026-04-11

Research Evidence

21 Research Sources
53 Avg Quality Score
11 Systematic Review
6 Rct
4 Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018
PubMed DOI
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001
PubMed Cochrane
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002
PubMed Cochrane
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024
PubMed DOI
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025
PubMed DOI
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023
PubMed
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025
PubMed DOI
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010
PubMed
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020
PubMed DOI
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025
PubMed DOI
View all evidence for 5 Htp →

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