Glucosamine Chondroitin with MSM Orange by The Vitamin Shoppe — Ingredients, Evidence & Safety

🟢 100/100

This product looks safe

No ingredients exceed tolerable upper intake levels
40% of ingredients have research evidence

A Label Compliance Grade

Product Label

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Label Data

15 mL Serving Size

32 Servings

Other Combinations Product Type

40% Evidence Coverage

Supplement Facts — Evidence Check

Calories

40 Calorie(s)

Total Carbohydrates

10 Gram(s) (4% DV)

Zinc

1.6 mg (15% DV)

✅ Within RDA (0.1× RDA of 11 mg) 📚 258 studies (Tier A: 6, B: 134)

RDA 11mg This product: 1.6mg UL 40mg

Manganese

0.9 mg (39% DV)

✅ Within RDA (0.4× RDA of 2.3 mg) 📚 8 studies — no high-quality reviews

RDA 2.3mg This product: 0.9mg UL 11mg

Sodium

21 mg (1% DV)

Glucosamine

1500 mg

📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)

This product: 1500mg

MSM

750 mg

📊 Market median: 1000.0mg (2 products)

This product: 750mg

Chondroitin Sulfate Sodium

300 mg

📊 Market median: 600.0mg (79 products) 📚 24 studies (Tier A: 0, B: 6)

This product: 300mg

Green Tea extract

100 mg

📊 Market median: 260.0mg (249 products) 📚 156 studies (Tier A: 4, B: 61)

This product: 100mg

Boron

50 mcg

📊 Market median: 3.0mg (58 products) 📚 2 studies — no high-quality reviews

This product: 0.05mg UL 20mg

Other Ingredients

Vegetable Glycerin purified Water Natural Flavors Xanthan Gum Citric Acid Malic Acid Luo Han extract Quick-Sorb

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (100% of products) Structure/Function (89% of products) Nutrient (16% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Directions: Take one (1) tablespoon (15 mL) daily. May be mixed with water or food.

⚠️ Warnings & Precautions

Contains: Crustacean Shellfish (shrimp, crab).

Warning: Do not use this product if you are nursing, pregnant, allergic to shellfish or sulfur.

Warning: Do not use this product if you are nursing, pregnant, allergic to shellfish or sulfur. Consult your physician prior to use if you are taking any medications especially anticoagulants or if you have any medical conditions especially diabetes.

Keep out of reach of children.

Tamper evident Do not use if outer seal is broken or missing.

🧪 Formulation Notes

No artificial colors, flavors or sweeteners

Joint support Mobility and flexibility

Gluten-free Dairy-free Soy-free Nut-free

This formula combines Glucosamine with Chondroitin, MSM and other joint-friendly nutrients to support the maintenance of healthy joint cartilage

Quik-Sorb is an exclusive blend of ingredients designed to support absorption.

Additional Information

Speciality

Quality Promise Tested & Trusted

Store in a cool, dry place.

Product Details

UPC / SKU 7 66536 02412 4

DSLD Entry Date 2020-04-23

Product Type Other Combinations

Form Liquid

Brand The Vitamin Shoppe

DSLD ID 217979

Data Updated 2026-04-11

Research Evidence

39 Research Sources

50 Avg Quality Score

20 Rct

9 Meta Analysis

4 Clinical Trial

3 Systematic Review

1 Regulatory Source

1 Openfda Safety

B Interventions for the management of temporomandibular joint osteoarthritis

Systematic Review The Cochrane database of systematic reviews 2012

PubMed DOI Cochrane

B Glucosamine therapy for treating osteoarthritis

Meta Analysis The Cochrane database of systematic reviews 2005

PubMed Cochrane

B Chondroitin for osteoarthritis

Meta Analysis The Cochrane database of systematic reviews 2015

PubMed DOI Cochrane

B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis

Meta Analysis Archives of orthopaedic and trauma surgery 2023

PubMed DOI

B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis

Rct The New England journal of medicine 2006

PubMed

B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review

Systematic Review International journal of molecular sciences 2023

PubMed DOI

B Scientific Opinion on glucosamine and joint health

Regulatory Source EFSA Journal 2009

DOI

B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis

Meta Analysis Computational and mathematical methods in medicine 2022

PubMed DOI

B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib

Rct Annals of the rheumatic diseases 2016

PubMed DOI

B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials

Meta Analysis Journal of orthopaedic surgery and research 2018

PubMed DOI

View all evidence for Glucosamine →