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EZ Flex

product on market Tablet or Pill Metagenics Safety: 89/100
89/100

This product is generally safe

  • Niacin: 250mg is 7.1× the Tolerable Upper Intake Level (35mg)
  • Folate: 665mg is 665.0× the Tolerable Upper Intake Level (1.0mg)
  • 100% of ingredients have research evidence
D Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

This formula contains B vitamins that support cellular energy production and metabolic function. Research provides strong evidence for the role of these nutrients in maintaining neurological health and homocysteine levels. However, the overall evidence coverage for this specific ingredient combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 250mg is 7.1× the Tolerable Upper Intake Level (35mg)

Folate: 665mg is 665.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for EZ Flex
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
60
Servings
Botanical with Nutrients
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

36 mg (2769% DV)
27.7× RDA — above typical dose 13 studies (A:0, B:1)
250 mg (1563% DV)
Exceeds UL by 7.1× (UL: 35 mg) 196 studies (A:5, B:63)
50 mg (2941% DV)
38.5× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
665 mcg DFE (166% DV)
Exceeds UL by 665.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
200 mcg (8333% DV)
83.3× RDA — above typical dose 139 studies (A:1, B:44)
50 mg (12% DV)
Within RDA (0.1× RDA) 316 studies (A:8, B:159)
Market median: 450.0mg (254 products) 243 studies (A:0, B:100)

Other Ingredients

Microcrystalline Cellulose Cellulose Stearic Acid Silica Croscarmellose Sodium Coating
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take on tablet twice daily or as directed by your healthcare practitioner.

Warnings & Precautions

Caution: If pregnant, nursing, or taking medication, consult your healthcare practitioner before use.

Keep out of the reach of children.

Formulation Notes

EZ Flex features high potency B vitamins as well as magnesium, and the herb turmeric in a formula designed to nutritionally support muscle tissue health.

This product is non-GMO, gluten-free, and vegetarian.

This product is non-GMO, gluten-free, and vegetarian.

Nutritonal support for muscle health

Additional Information

Storage: Keep tightly closed in a cool, dry place.

GF Certified Gluten-free

Practitioner exclusive

Metadata

Product Details

UPC / SKU7 55571 01595 2
DSLD Entry Date2020-03-24
Product TypeBotanical with Nutrients
FormTablet or Pill
BrandMetagenics
DSLD ID216348
Data Updated2026-04-11
Research

Research Evidence

22
Research Sources
49
Avg Quality
8
Rct
4
Meta Analysis
4
Clinical Trial
3
Systematic Review
1
Cochrane Review
1
Regulatory Source
B Effect of vitamin B2, vitamin C, vitamin D, vitamin E and folic acid in adults with essential hypertension: a systematic review and network meta-analysis
Systematic Review BMJ open 2024 PubMed DOI
B Effect of Vitamin B2 supplementation on migraine prophylaxis: a systematic review and meta-analysis
Meta Analysis Nutritional neuroscience 2022 PubMed DOI
B Supplementary vitamin E, selenium, cysteine and riboflavin for preventing kwashiorkor in preschool children in developing countries
Systematic Review The Cochrane database of systematic reviews 2010 PubMed DOI
B Riboflavin supplements for blood pressure lowering in adults.
Cochrane Review The Cochrane database of systematic reviews PubMed DOI
B Associations of dietary vitamin B1, vitamin B2, vitamin B6, and vitamin B12 with the risk of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2022 PubMed DOI
C Prophylaxis of migraine headaches with riboflavin: A systematic review
Systematic Review Journal of clinical pharmacy and therapeutics 2017 PubMed DOI
C Medium-dose riboflavin as a prophylactic agent in children with migraine: a preliminary placebo-controlled, randomised, double-blind, cross-over trial
Rct Cephalalgia : an international journal of headache 2010 PubMed DOI
C The efficacy of 2 different phakic intraocular lens implant in keratoconus as an isolated procedure or combined with collagen crosslinking and intra-stromal corneal ring segments: a systematic review and meta-analysis
Meta Analysis International ophthalmology 2023 PubMed DOI
C Epithelium-off photochemical corneal collagen cross-linkage using riboflavin and ultraviolet a for keratoconus and keratectasia: a systematic review and meta-analysis
Meta Analysis The ocular surface 2014 PubMed DOI
C Improvement of migraine symptoms with a proprietary supplement containing riboflavin, magnesium and Q10: a randomized, placebo-controlled, double-blind, multicenter trial
Rct The journal of headache and pain 2015 PubMed DOI
View all evidence for Riboflavin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.