🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 67% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Capsule(s) Serving Size
60 Servings
Other Combinations Product Type
67% Evidence Coverage

Supplement Facts — Evidence Check

Calcium
20 mg (2% DV)
200 mg
✅ Within RDA (0.4× RDA of 550 mg) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 200mg UL 3500mg
✅ Within RDA (0.1× RDA of 700 mg) 📚 12 studies (Tier A: 0, B: 3)
RDA 700mg This product: 75mg UL 4000mg

Other Ingredients

Hydroxypropyl Methylcellulose Microcrystalline Cellulose Stearic Acid Silica Magnesium Stearate

Label Claims — Verification

All Other
Structure/Function
All Other (97% of products) Structure/Function (90% of products) Nutrient (42% of products)

Target Groups

Adult (18 - 50 Years) Women (not pregnant or lactating)

Product Information

📋 Directions for Use

Directions: Adults take 1 capsule up to 6 times daily, as a dietary supplement or as recommended by your doctor.

⚠️ Warnings & Precautions

Warning: Use only as directed. Not for use by pregnant or lactating women. Consult a doctor before use if you are taking medications or have a medical condition.

Not intended for children.

Keep out of the reach of children.

Do not use if clear safety seal around bottle neck is broken or missing.

🧪 Formulation Notes

Roex Choline Supreme provides a superior form of choline (GPC) which is more effective at enhancing brain neurotransmitter levels than traditional choline or lecithin supplements. Also contains uridine, a natural nucleic acid that promotes the conversion of choline to membrane phospholipids, greatly enhancing the immediate and long-term benefits of GPC.

Cognitive support with uridine Increases neurotransmitter release Enhances memory and brain function Slows brain aging

Additional Information

Store at room temperature, in a dry place.

Product Details

UPC / SKU 6 45245 87060 7
DSLD Entry Date 2020-01-25
Product Type Other Combinations
Form Capsule
Brand Roex
DSLD ID 211523
Data Updated 2026-04-11

Research Evidence

28 Research Sources
47 Avg Quality Score
11 Clinical Trial
8 Rct
2 Guideline
2 Meta Analysis
2 Regulatory Source
1 Systematic Review
1 Openfda Safety
B Greater Choline-Containing Compounds and Myo-inositol in Treatment-Resistant Versus Responsive Schizophrenia: A 1H-Magnetic Resonance Spectroscopy Meta-analysis
Meta Analysis Biological psychiatry. Cognitive neuroscience and neuroimaging 2024
B Integrating multi-structure covalent docking with machine-learning consensus scoring enhances potency ranking of human acetylcholinesterase inhibitors.
Guideline Briefings in bioinformatics 2026
B Evidence-based clinical practice guidelines for functional dyspepsia 2021.
Guideline Journal of gastroenterology 2022
B Scientific Opinion on health claims related to choline
Regulatory Source EFSA Journal 2011
C Effectiveness of nutritional interventions to prevent nonprogressive congenital and perinatal brain injuries: a systematic review and meta-analysis of randomized trials
Meta Analysis Nutrition reviews 2022
C Two methods for assessment of choline status in a randomized crossover study with varying dietary choline intake in people: isotope dilution MS of plasma and in vivo single-voxel magnetic resonance spectroscopy of liver.
Rct The American journal of clinical nutrition
C Choline and betaine concentrations in plasma discriminate levels of dietary choline intake in healthy adults: analysis of a double-blind randomized crossover controlled feeding study.
Rct The American journal of clinical nutrition
C Nutrient-based therapies for bipolar disorder: a systematic review
Systematic Review Psychotherapy and psychosomatics 2013
C The association of betaine, homocysteine and related metabolites with cognitive function in Dutch elderly people
Rct The British journal of nutrition 2007
C Differential metabolism of choline supplements in adult volunteers.
Rct European journal of nutrition
View all evidence for Choline →

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