100/100
This product looks safe
- No ingredients exceed tolerable upper intake levels
- 67% of ingredients have research evidence
A
Label Compliance Grade
What the Evidence Says
✨ AI-generated · Qwen 3.6
· methodology
Alpha-GPC and uridine 5'-monophosphate are researched for their roles in supporting cognitive function and neurotransmitter synthesis, though evidence for these specific combinations is limited. Calcium serves as a fundamental mineral for cellular signaling. Overall, the evidence coverage for this specific ingredient profile is very low.
AI-generated summary based on research evidence. Not medical advice.
Details
Label Data
1 Capsule(s)
Serving Size
Other Combinations
Product Type
Ingredients
Supplement Facts — Evidence Check
Within RDA (0.4× RDA)
38 studies (A:1, B:7)
Within RDA (0.1× RDA)
13 studies (A:0, B:3)
Other Ingredients
Hydroxypropyl Methylcellulose
Microcrystalline Cellulose
Stearic Acid
Silica
Magnesium Stearate
Claims
Label Claims — Verification
Unverified
All Other
Unverified
Structure/Function
Info
Product Information
Directions for Use
Directions: Adults take 1 capsule up to 6 times daily, as a dietary supplement or as recommended by your doctor.
Warnings & Precautions
Warning: Use only as directed. Not for use by pregnant or lactating women. Consult a doctor before use if you are taking medications or have a medical condition.
Not intended for children.
Keep out of the reach of children.
Do not use if clear safety seal around bottle neck is broken or missing.
Formulation Notes
Roex Choline Supreme provides a superior form of choline (GPC) which is more effective at enhancing brain neurotransmitter levels than traditional choline or lecithin supplements. Also contains uridine, a natural nucleic acid that promotes the conversion of choline to membrane phospholipids, greatly enhancing the immediate and long-term benefits of GPC.
Cognitive support with uridine
Increases neurotransmitter release
Enhances memory and brain function
Slows brain aging
Additional Information
Store at room temperature, in a dry place.
Metadata
Product Details
UPC / SKU6 45245 87060 7
DSLD Entry Date2020-01-25
Product TypeOther Combinations
FormCapsule
Data Updated2026-04-11
Research
Research Evidence
B
Greater Choline-Containing Compounds and Myo-inositol in Treatment-Resistant Versus Responsive Schizophrenia: A 1H-Magnetic Resonance Spectroscopy Meta-analysis
Meta Analysis
Biological psychiatry. Cognitive neuroscience and neuroimaging
2024
PubMed
DOI
B
Integrating multi-structure covalent docking with machine-learning consensus scoring enhances potency ranking of human acetylcholinesterase inhibitors.
Guideline
Briefings in bioinformatics
2026
PubMed
DOI
B
Evidence-based clinical practice guidelines for functional dyspepsia 2021.
Guideline
Journal of gastroenterology
2022
PubMed
DOI
B
Scientific Opinion on health claims related to choline
Regulatory Source
EFSA Journal
2011
DOI
C
Effectiveness of nutritional interventions to prevent nonprogressive congenital and perinatal brain injuries: a systematic review and meta-analysis of randomized trials
Meta Analysis
Nutrition reviews
2022
PubMed
DOI
C
Two methods for assessment of choline status in a randomized crossover study with varying dietary choline intake in people: isotope dilution MS of plasma and in vivo single-voxel magnetic resonance spectroscopy of liver.
Rct
The American journal of clinical nutrition
PubMed
DOI
C
Choline and betaine concentrations in plasma discriminate levels of dietary choline intake in healthy adults: analysis of a double-blind randomized crossover controlled feeding study.
Rct
The American journal of clinical nutrition
PubMed
DOI
C
Nutrient-based therapies for bipolar disorder: a systematic review
Systematic Review
Psychotherapy and psychosomatics
2013
PubMed
DOI
C
The association of betaine, homocysteine and related metabolites with cognitive function in Dutch elderly people
Rct
The British journal of nutrition
2007
PubMed
C
Differential metabolism of choline supplements in adult volunteers.
View all evidence for Choline →
This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.
