🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

2 Capsule(s) Serving Size
60 Servings
Other Combinations Product Type
50% Evidence Coverage

Supplement Facts — Evidence Check

📊 Market median: 496.0mg (192 products) 📚 20 studies — no high-quality reviews
This product: 500mg
✅ 1.8× RDA — within safe limits 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 1000mg UL 3500mg

Other Ingredients

Hydroxypropyl Methylcellulose Stearic Acid Silica Magnesium Stearate

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (97% of products) Structure/Function (90% of products) Nutrient (42% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Directions: Adults, take 2 capsules in the morning with breakfast and 2 capsules with dinner, with 8 ounces of water. Take as dietary supplement or as directed by your doctor.

⚠️ Warnings & Precautions

Warning: Consult your physician prior to use if you are pregnant, nursing, have a medical condition or are taking medications.

Not intended for children.

Keep out of the reach of children.

Do not use if clear safety seal around bottle neck is broken or missing.

🧪 Formulation Notes

Choline Bitartrate allows the body to manufacture the neurotransmitter acetylcholine, which assists in bladder, kidney, pancreatic, testicular, and liver functions. It also aids in hormone production and has been shown to help boost the libido. Roex has added Betaine HCl to help increase the secretion of HCl from the stomach's parietal cells, which is critical for proper digestion of proteins and the emulsification of fats.

Essential for healthy brain, memory and nerve function Supports healthy bladder and kidney function

Contains Betaine HCl for proper digestion and breakdown of proteins and fats

Additional Information

Store at room temperature, in a dry place.

Product Details

UPC / SKU 0 45245 37120 1
DSLD Entry Date 2020-01-25
Product Type Other Combinations
Form Capsule
Brand Roex
DSLD ID 211487
Data Updated 2026-04-11

Research Evidence

28 Research Sources
47 Avg Quality Score
11 Clinical Trial
8 Rct
2 Guideline
2 Meta Analysis
2 Regulatory Source
1 Systematic Review
1 Openfda Safety
B Greater Choline-Containing Compounds and Myo-inositol in Treatment-Resistant Versus Responsive Schizophrenia: A 1H-Magnetic Resonance Spectroscopy Meta-analysis
Meta Analysis Biological psychiatry. Cognitive neuroscience and neuroimaging 2024
B Integrating multi-structure covalent docking with machine-learning consensus scoring enhances potency ranking of human acetylcholinesterase inhibitors.
Guideline Briefings in bioinformatics 2026
B Evidence-based clinical practice guidelines for functional dyspepsia 2021.
Guideline Journal of gastroenterology 2022
B Scientific Opinion on health claims related to choline
Regulatory Source EFSA Journal 2011
C Effectiveness of nutritional interventions to prevent nonprogressive congenital and perinatal brain injuries: a systematic review and meta-analysis of randomized trials
Meta Analysis Nutrition reviews 2022
C Two methods for assessment of choline status in a randomized crossover study with varying dietary choline intake in people: isotope dilution MS of plasma and in vivo single-voxel magnetic resonance spectroscopy of liver.
Rct The American journal of clinical nutrition
C Choline and betaine concentrations in plasma discriminate levels of dietary choline intake in healthy adults: analysis of a double-blind randomized crossover controlled feeding study.
Rct The American journal of clinical nutrition
C Nutrient-based therapies for bipolar disorder: a systematic review
Systematic Review Psychotherapy and psychosomatics 2013
C The association of betaine, homocysteine and related metabolites with cognitive function in Dutch elderly people
Rct The British journal of nutrition 2007
C Differential metabolism of choline supplements in adult volunteers.
Rct European journal of nutrition
View all evidence for Choline →

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