Brilliant Brain

product on market Tablet or Pill 21st Century 🟢 Safety: 100/100
Brand: 21st Century
🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 71% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

2 Tablet(s) Serving Size
30 Servings
Other Combinations Product Type
71% Evidence Coverage

Supplement Facts — Evidence Check

Calcium
130 mg (10% DV)
250 mg
✅ Within RDA (0.5× RDA of 550 mg) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 250mg UL 3500mg
100 mg
📊 Market median: 200.0mg (358 products) 📚 9 studies (Tier A: 0, B: 2)
This product: 100mg
100 mg
📊 Market median: 120.0mg (440 products) 📚 187 studies (Tier A: 1, B: 71)
This product: 100mg
50 mg
📊 Market median: 180.0mg (239 products) 📚 43 studies (Tier A: 1, B: 19)
This product: 50mg UL 400mg
25 mg
📊 Market median: 450.0mg (254 products) 📚 240 studies (Tier A: 0, B: 100)
This product: 25mg
Bioperine
5 mg

Other Ingredients

Cellulose Croscarmellose Sodium Stearic Acid Silicon Dioxide Contains Less Than 2% of

Label Claims — Verification

❓ All Other
❓ Structure/Function
All Other (99% of products) Structure/Function (85% of products) Nutrient (54% of products) Approved Health (3% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Directions: As a dietary supplement, adults take two (2) tablets daily with any meal or as directed by a healthcare provider. Do not exceed recommended dosage.

For best results, take daily.

⚠️ Warnings & Precautions

Do not exceed recommended dosage.

Warning: Consult a healthcare provider prior to use if pregnant, nursing, on medications, have a medical condition, including neurologic, neuromuscular, psychiatric or movement disorders, or are planning a medical procedure.

Stop use and contact a physician if adverse reactions occur.

This product contains caffeine. Avoid additional consumption of caffeine, which may cause adverse effects.

Keep out of reach of children.

Do not use if product appears to be tampered with or seal is broken.

🧪 Formulation Notes

This product contains caffeine.

Cognitive Health & Focus Support 21st Century Brilliant Brain is formulated with Cognizin Citicoline plus Ginkgo Biloba and Turmeric Extract to help support the normal functions of cognitive health and focus support.

With Cognizin Plus Ginkgo Biloba & Turmeric Extract

Gluten free

No added Sugar, Yeast, Preservatives or Artificial Flavors.

Additional Information

Individual results may vary.

Store at room temperature.

Guaranteed quality Laboratory tested

Focused results

Gluten free

Get focused results Cognitive health support Overall focus support Brain function support

91652-501481-0219N

Product Details

UPC / SKU 7 40985 27933 5
DSLD Entry Date 2019-08-23
Product Type Other Combinations
Form Tablet or Pill
Brand 21st Century
DSLD ID 205530
Data Updated 2026-04-11

Research Evidence

849 Research Sources
56 Avg Quality Score
450 Meta Analysis
152 Rct
137 Systematic Review
73 Clinical Trial
11 Regulatory Source
7 Other
7 Guideline
3 Openfda Safety
2 Cochrane Review
2 Observational
A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)
Meta Analysis The Cochrane database of systematic reviews 2018
PubMed DOI Cochrane
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024
PubMed DOI Cochrane
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015
PubMed DOI Cochrane
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018
PubMed DOI Cochrane
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025
PubMed DOI Cochrane
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008
PubMed DOI Cochrane
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023
PubMed DOI Cochrane
A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019
PubMed DOI
A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021
PubMed DOI
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021
PubMed DOI
View all evidence for Electrolytes →

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