🟢 92/100

This product looks safe

  • Vitamin B3: 125mg is 3.6× the Tolerable Upper Intake Level (35mg)
  • Folate: 1667mg is 1667.0× the Tolerable Upper Intake Level (1.0mg)
  • 56% of ingredients have research evidence
D Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Vitamin B3: 125mg is 3.6× the Tolerable Upper Intake Level (35mg)
⚠️ Folate: 1667mg is 1667.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

1 Tablet(s) Serving Size
60 Servings
Other Combinations Product Type
56% Evidence Coverage

Supplement Facts — Evidence Check

50 mg (4170% DV)
📊 41.7× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 50mg
125 mg (780% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 3.6× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 125mg UL 35mg
10 mg (590% DV)
📊 7.7× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 10mg UL 100mg
1667 mcg DFE (420% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1667.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 1667mg UL 1.0mg
500 mcg (20830% DV)
📊 208.3× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.5mg
125 mg (2500% DV)
📊 25.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 125mg
Dimethylaminoethanol Bitartrate
150 mg
📊 Market median: 100.0mg (108 products)
Median 100.0mg This product: 25mg
Toothed Clubmoss extract
7.5 mg

Other Ingredients

Cellulose Mono and Diglycerides Dibasic Calcium Phosphate Carob Cellulose Gum Silicon Dioxide Stearic Acid Magnesium Stearate Maltodextrin Methylcellulose Glycerin natural food Glaze Hypromellose

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (47% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) Dairy Free

Product Information

📋 Directions for Use

Directions: Take 1 tablet, two times daily, preferably in the morning and afternoon, with a meal. Do not exceed recommended daily intake.

⚠️ Warnings & Precautions

Contains: Soy

Warning: Consult your healthcare professional prior to use if you have or suspect a medical condition or are taking prescription drugs. Do not use if you are pregnant or lactating.

Not for use by individuals under the age of 18 years.

Keep out of reach of children.

Do not exceed recommended daily intake.

🧪 Formulation Notes

Contains: Soy

No: Milk, Egg, Fish, Crustacean Shellfish, Tree Nuts, Peanuts, Wheat, Yeast, Artificial Colors, Flavors, or Added Sugar

Vegetarian

Additional Information

Natrol BrainSpeed Memory Supports brain health Helps maintain memory Promotes recall

Store in a cool, dry place.

ITEM: 4365.911 F: 3001387 L: 2008955-17215

Vegetarian

Product Details

UPC / SKU 0 47469 04365 0
DSLD Entry Date 2019-05-28
Product Type Other Combinations
Form Tablet or Pill
Brand Natrol
DSLD ID 203036
Data Updated 2026-04-11

Research Evidence

100 Research Sources
56 Avg Quality Score
48 Systematic Review
30 Meta Analysis
13 Rct
6 Clinical Trial
1 Cochrane Review
1 Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004
View all evidence for Thiamine →

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