Home/ Supplements/ Niacin/ Chol-Less Max

Chol-Less Max

product on market Capsule HoltraCeuticals Safety: 95/100
95/100

This product looks safe

  • Niacin: 1080mg is 30.9× the Tolerable Upper Intake Level (35mg)
  • 75% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains berberine and chromium, which have moderate to strong evidence for supporting healthy blood glucose and lipid levels. Niacin and inositol hexaniacinate are traditionally used to manage cholesterol, though evidence for some combined effects remains limited. The profile maintains a high safety score with minimal reported concerns.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 1080mg is 30.9× the Tolerable Upper Intake Level (35mg)

Label

Product Label

Label for Chol-Less Max
Open Full PDF View on NIH DSLD →
Details

Label Data

3 Capsule(s)
Serving Size
45
Servings
Other Combinations
Product Type
75%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

1080 mg (5625% DV)
Exceeds UL by 30.9× (UL: 35 mg) 196 studies (A:5, B:63)
1 mg (833% DV)
28.6× RDA — above typical dose 199 studies (A:1, B:55)
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
Market median: 500.0mg (234 products) 95 studies (A:0, B:35)
Artichoke (leaf) extract
45 mg
Policosanol
36 mg
Market median: 500.0mg (497 products) 135 studies (A:0, B:40)

Other Ingredients

Gelatin Magnesium Stearate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use: As a dietary supplement, 3-6 capsules per day or as directed by your physician.

Warnings & Precautions

Warning: If you are under medical supervision, seek the advice of your physician or healthcare professional prior to use of this product. Individuals with autoimmune conditions, depressive disorders or pregnant/lactating women should consult their physician prior to use.

Keep out of reach of children.

Transient ushing of the skin can follow ingestion of niacin, especially if taken with little or no food.

Additional Information

*Synergistic Cholesterol Lowering Formula

Store in a cool, dry place protected from light.

Metadata

Product Details

UPC / SKU8 37654 69357 5
DSLD Entry Date2013-03-25
Product TypeOther Combinations
FormCapsule
BrandHoltraCeuticals
DSLD ID19374
Data Updated2026-04-11
Research

Research Evidence

241
Research Sources
55
Avg Quality
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024 PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010 PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010 PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019 PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016 PubMed DOI
View all evidence for Niacin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.