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MigreLief+M

product on market Other (e.g. tea bag) Akeso Safety: 95/100
95/100

This product looks safe

  • Magnesium: 360mg is 1.0× the Tolerable Upper Intake Level (350mg)
  • 75% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Riboflavin and magnesium have moderate to strong evidence for reducing migraine frequency and severity. L-theanine and B-vitamins support neurological function and stress response, though evidence for migraine prevention is more limited. The profile maintains a high safety score with minimal reported concerns.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Magnesium: 360mg is 1.0× the Tolerable Upper Intake Level (350mg)

Label

Product Label

Label for MigreLief+M
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Caplet(s)
Serving Size
Other Combinations
Product Type
75%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

400 mg (23520% DV)
307.7× RDA — above typical dose 13 studies (A:0, B:1)
360 mg (90% DV)
Exceeds UL by 1.0× (UL: 350 mg) 316 studies (A:8, B:159)
100 mg (5000% DV)
76.9× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
15 mg (4950% DV)
500.0× RDA — above typical dose 27 studies (A:0, B:11)
100 mg
Market median: 200.0mg (358 products) 9 studies (A:0, B:2)
1000 mcg
28.6× RDA — above typical dose 199 studies (A:1, B:55)
Chasteberry extract
275 mg
Market median: 380.0mg (120 products) 8 studies — no high-quality reviews

Other Ingredients

powdered Cellulose Grape seed extract Dextrates Vegetable Gum Stearic Acid Sodium Starch Glycolate Silicon Dioxide Hydroxypropyl Methylcellulose Titanium Dioxide Carmine microfine Wax
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Recommended Usage: Take 1 caplet twice a day - with food. MigreLief+M is designed to provide benefits within the 90 day build up period. To maintain benefits, continue daily use - For on the spot support, try adding MigreLief-NOW as-needed.

Warnings & Precautions

Warnings: MigreLief+M is just for women and is not recommended during pregnancy and lactation or for young females who are not yet menstruating.

Formulation Notes

Warnings: MigreLief+M is just for women and is not recommended during pregnancy and lactation or for young females who are not yet menstruating.

Does not contain: Yeast, milk, corn, wheat, gluten, soy, salt, artificial flavorings or preservatives.

Menstrual Formula

Puracol is a proprietary combination of whole leaf feverfew that is high in naturally occurring phytochemicals and a unique feverfew extract.

Additional Information

MigreLief+M is a specific reformulation of the patented MigreLief Original Formula recommended by headache specialists.

MigreLief+M works to maintain hormonal and blood sugar balance that can be disrupted during PMS and just before or after menstruation.

Where nature & medicine unite

Recommended by top headache doctors to provide nutritional support for migraine sufferers

Metadata

Product Details

UPC / SKU8 55586 00062 9
DSLD Entry Date2019-01-07
Product TypeOther Combinations
FormOther (e.g. tea bag)
BrandAkeso
DSLD ID183028
Data Updated2026-04-11
Research

Research Evidence

22
Research Sources
49
Avg Quality
8
Rct
4
Meta Analysis
4
Clinical Trial
3
Systematic Review
1
Cochrane Review
1
Regulatory Source
B Effect of vitamin B2, vitamin C, vitamin D, vitamin E and folic acid in adults with essential hypertension: a systematic review and network meta-analysis
Systematic Review BMJ open 2024 PubMed DOI
B Effect of Vitamin B2 supplementation on migraine prophylaxis: a systematic review and meta-analysis
Meta Analysis Nutritional neuroscience 2022 PubMed DOI
B Supplementary vitamin E, selenium, cysteine and riboflavin for preventing kwashiorkor in preschool children in developing countries
Systematic Review The Cochrane database of systematic reviews 2010 PubMed DOI
B Riboflavin supplements for blood pressure lowering in adults.
Cochrane Review The Cochrane database of systematic reviews PubMed DOI
B Associations of dietary vitamin B1, vitamin B2, vitamin B6, and vitamin B12 with the risk of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2022 PubMed DOI
C Prophylaxis of migraine headaches with riboflavin: A systematic review
Systematic Review Journal of clinical pharmacy and therapeutics 2017 PubMed DOI
C Medium-dose riboflavin as a prophylactic agent in children with migraine: a preliminary placebo-controlled, randomised, double-blind, cross-over trial
Rct Cephalalgia : an international journal of headache 2010 PubMed DOI
C The efficacy of 2 different phakic intraocular lens implant in keratoconus as an isolated procedure or combined with collagen crosslinking and intra-stromal corneal ring segments: a systematic review and meta-analysis
Meta Analysis International ophthalmology 2023 PubMed DOI
C Epithelium-off photochemical corneal collagen cross-linkage using riboflavin and ultraviolet a for keratoconus and keratectasia: a systematic review and meta-analysis
Meta Analysis The ocular surface 2014 PubMed DOI
C Improvement of migraine symptoms with a proprietary supplement containing riboflavin, magnesium and Q10: a randomized, placebo-controlled, double-blind, multicenter trial
Rct The journal of headache and pain 2015 PubMed DOI
View all evidence for Riboflavin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.