🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 75% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

2 Caplet(s) Serving Size
Other Combinations Product Type
75% Evidence Coverage

Supplement Facts — Evidence Check

400 mg (23520% DV)
📊 307.7× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 400mg
360 mg (90% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 360mg
100 mg (5000% DV)
📊 76.9× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 100mg UL 100mg
15 mg (4950% DV)
📊 500.0× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 15mg
100 mg
📊 Market median: 200.0mg (358 products) 📚 9 studies (Tier A: 0, B: 2)
This product: 100mg
1000 mcg
📊 28.6× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 1.0mg
Chasteberry extract
275 mg
📊 Market median: 380.0mg (120 products) 📚 8 studies — no high-quality reviews
This product: 100mg

Other Ingredients

powdered Cellulose Grape seed extract Dextrates Vegetable Gum Stearic Acid Sodium Starch Glycolate Silicon Dioxide Hydroxypropyl Methylcellulose Titanium Dioxide Carmine microfine Wax

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (85% of products) Nutrient (48% of products) No Claim (1% of products)

Target Groups

Women (not pregnant or lactating) Adult Female (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Recommended Usage: Take 1 caplet twice a day - with food. MigreLief+M is designed to provide benefits within the 90 day build up period. To maintain benefits, continue daily use - For on the spot support, try adding MigreLief-NOW as-needed.

⚠️ Warnings & Precautions

Warnings: MigreLief+M is just for women and is not recommended during pregnancy and lactation or for young females who are not yet menstruating.

🧪 Formulation Notes

Warnings: MigreLief+M is just for women and is not recommended during pregnancy and lactation or for young females who are not yet menstruating.

Does not contain: Yeast, milk, corn, wheat, gluten, soy, salt, artificial flavorings or preservatives.

Menstrual Formula

Puracol is a proprietary combination of whole leaf feverfew that is high in naturally occurring phytochemicals and a unique feverfew extract.

Additional Information

MigreLief+M is a specific reformulation of the patented MigreLief Original Formula recommended by headache specialists.

MigreLief+M works to maintain hormonal and blood sugar balance that can be disrupted during PMS and just before or after menstruation.

Where nature & medicine unite

Recommended by top headache doctors to provide nutritional support for migraine sufferers

Product Details

UPC / SKU 8 55586 00062 9
DSLD Entry Date 2019-01-07
Product Type Other Combinations
Form Other (e.g. tea bag)
Brand Akeso
DSLD ID 183028
Data Updated 2026-04-11

Research Evidence

22 Research Sources
49 Avg Quality Score
8 Rct
4 Meta Analysis
4 Clinical Trial
3 Systematic Review
1 Cochrane Review
1 Regulatory Source
B Effect of vitamin B2, vitamin C, vitamin D, vitamin E and folic acid in adults with essential hypertension: a systematic review and network meta-analysis
Systematic Review BMJ open 2024
B Effect of Vitamin B2 supplementation on migraine prophylaxis: a systematic review and meta-analysis
Meta Analysis Nutritional neuroscience 2022
B Supplementary vitamin E, selenium, cysteine and riboflavin for preventing kwashiorkor in preschool children in developing countries
Systematic Review The Cochrane database of systematic reviews 2010
B Riboflavin supplements for blood pressure lowering in adults.
Cochrane Review The Cochrane database of systematic reviews
B Associations of dietary vitamin B1, vitamin B2, vitamin B6, and vitamin B12 with the risk of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2022
C Prophylaxis of migraine headaches with riboflavin: A systematic review
Systematic Review Journal of clinical pharmacy and therapeutics 2017
C Medium-dose riboflavin as a prophylactic agent in children with migraine: a preliminary placebo-controlled, randomised, double-blind, cross-over trial
Rct Cephalalgia : an international journal of headache 2010
C The efficacy of 2 different phakic intraocular lens implant in keratoconus as an isolated procedure or combined with collagen crosslinking and intra-stromal corneal ring segments: a systematic review and meta-analysis
Meta Analysis International ophthalmology 2023
C Epithelium-off photochemical corneal collagen cross-linkage using riboflavin and ultraviolet a for keratoconus and keratectasia: a systematic review and meta-analysis
Meta Analysis The ocular surface 2014
C Improvement of migraine symptoms with a proprietary supplement containing riboflavin, magnesium and Q10: a randomized, placebo-controlled, double-blind, multicenter trial
Rct The journal of headache and pain 2015
View all evidence for Riboflavin →

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