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MigreLief Triple Therapy with Puracol

product on market Other (e.g. tea bag) Akeso Safety: 87/100
87/100

This product is generally safe

  • Magnesium: 360mg is 1.0× the Tolerable Upper Intake Level (350mg)
  • 67% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Riboflavin and magnesium are supported by moderate evidence for reducing migraine frequency and severity. Puracol feverfew is used for its potential prophylactic effects, though clinical data for this specific extract is more limited. The combination targets multiple pathways to support neurological function.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Magnesium: 360mg is 1.0× the Tolerable Upper Intake Level (350mg)

Label

Product Label

Label for MigreLief Triple Therapy with Puracol
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Caplet(s)
Serving Size
Botanical with Nutrients
Product Type
67%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

400 mg (23520% DV)
307.7× RDA — above typical dose 13 studies (A:0, B:1)
360 mg (90% DV)
Exceeds UL by 1.0× (UL: 350 mg) 316 studies (A:8, B:159)
Market median: 380.0mg (120 products) 8 studies — no high-quality reviews

Other Ingredients

powdered Cellulose Grape seed extract Vegetable Gum Hydroxypropyl Methylcellulose Stearic Acid Sodium Starch Glycolate Silicon Dioxide Dextrates Titanium Dioxide Polyethylene Glycol natural Caramel color microfine Wax
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Recommended Usage: Take 1 caplet twice a day with food. MigreLief (daily formula) is designed to provide benefits within the 90 day build up period. Continue daily use to maintain benefits.

Warnings & Precautions

Warnings: This product is not recommended during pregnancy and lactation or for children under age 2.

Warnings: This product is not recommended during pregnancy and lactation or for children under age 2.

Consult with your healthcare professional before use.

Formulation Notes

Does not contain: Yeast, milk, corn, wheat, gluten, soy, salt, artificial flavorings or preservatives.

Puracol is a proprietary combination of whole leaf feverfew that is high in naturally occurring phytochemicals and a unique feverfew extract.

Additional Information

For on the spot support, try adding MigreLief-NOW as-needed. Questions? Email: HealthAdvisor@MigreLief.com

Where nature & medicine unite

Original formula

Recommended by top headache doctors to provide nutritional support for migraine sufferers

Metadata

Product Details

UPC / SKU8 55586 00022 3
DSLD Entry Date2018-11-21
Product TypeBotanical with Nutrients
FormOther (e.g. tea bag)
BrandAkeso
DSLD ID183021
Data Updated2026-04-11
Research

Research Evidence

22
Research Sources
49
Avg Quality
8
Rct
4
Meta Analysis
4
Clinical Trial
3
Systematic Review
1
Cochrane Review
1
Regulatory Source
B Effect of vitamin B2, vitamin C, vitamin D, vitamin E and folic acid in adults with essential hypertension: a systematic review and network meta-analysis
Systematic Review BMJ open 2024 PubMed DOI
B Effect of Vitamin B2 supplementation on migraine prophylaxis: a systematic review and meta-analysis
Meta Analysis Nutritional neuroscience 2022 PubMed DOI
B Supplementary vitamin E, selenium, cysteine and riboflavin for preventing kwashiorkor in preschool children in developing countries
Systematic Review The Cochrane database of systematic reviews 2010 PubMed DOI
B Riboflavin supplements for blood pressure lowering in adults.
Cochrane Review The Cochrane database of systematic reviews PubMed DOI
B Associations of dietary vitamin B1, vitamin B2, vitamin B6, and vitamin B12 with the risk of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2022 PubMed DOI
C Prophylaxis of migraine headaches with riboflavin: A systematic review
Systematic Review Journal of clinical pharmacy and therapeutics 2017 PubMed DOI
C Medium-dose riboflavin as a prophylactic agent in children with migraine: a preliminary placebo-controlled, randomised, double-blind, cross-over trial
Rct Cephalalgia : an international journal of headache 2010 PubMed DOI
C The efficacy of 2 different phakic intraocular lens implant in keratoconus as an isolated procedure or combined with collagen crosslinking and intra-stromal corneal ring segments: a systematic review and meta-analysis
Meta Analysis International ophthalmology 2023 PubMed DOI
C Epithelium-off photochemical corneal collagen cross-linkage using riboflavin and ultraviolet a for keratoconus and keratectasia: a systematic review and meta-analysis
Meta Analysis The ocular surface 2014 PubMed DOI
C Improvement of migraine symptoms with a proprietary supplement containing riboflavin, magnesium and Q10: a randomized, placebo-controlled, double-blind, multicenter trial
Rct The journal of headache and pain 2015 PubMed DOI
View all evidence for Riboflavin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.