🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 67% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

2 Caplet(s) Serving Size
Botanical with Nutrients Product Type
67% Evidence Coverage

Supplement Facts — Evidence Check

400 mg (23520% DV)
📊 307.7× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 400mg
360 mg (90% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 360mg
📊 Market median: 380.0mg (120 products) 📚 8 studies — no high-quality reviews
This product: 100mg

Other Ingredients

powdered Cellulose Grape seed extract Vegetable Gum Hydroxypropyl Methylcellulose Stearic Acid Sodium Starch Glycolate Silicon Dioxide Dextrates Titanium Dioxide Polyethylene Glycol natural Caramel color microfine Wax

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (85% of products) Nutrient (48% of products) No Claim (1% of products)

Target Groups

Children 4 or More Years of Age Adult (18 - 50 Years) Gluten Free Dairy Free Children more than 1 but less than 4

Product Information

📋 Directions for Use

Recommended Usage: Take 1 caplet twice a day with food. MigreLief (daily formula) is designed to provide benefits within the 90 day build up period. Continue daily use to maintain benefits.

⚠️ Warnings & Precautions

Warnings: This product is not recommended during pregnancy and lactation or for children under age 2.

Warnings: This product is not recommended during pregnancy and lactation or for children under age 2.

Consult with your healthcare professional before use.

🧪 Formulation Notes

Does not contain: Yeast, milk, corn, wheat, gluten, soy, salt, artificial flavorings or preservatives.

Puracol is a proprietary combination of whole leaf feverfew that is high in naturally occurring phytochemicals and a unique feverfew extract.

Additional Information

For on the spot support, try adding MigreLief-NOW as-needed. Questions? Email: HealthAdvisor@MigreLief.com

Where nature & medicine unite

Original formula

Recommended by top headache doctors to provide nutritional support for migraine sufferers

Product Details

UPC / SKU 8 55586 00022 3
DSLD Entry Date 2018-11-21
Product Type Botanical with Nutrients
Form Other (e.g. tea bag)
Brand Akeso
DSLD ID 183021
Data Updated 2026-04-11

Research Evidence

22 Research Sources
49 Avg Quality Score
8 Rct
4 Meta Analysis
4 Clinical Trial
3 Systematic Review
1 Cochrane Review
1 Regulatory Source
B Effect of vitamin B2, vitamin C, vitamin D, vitamin E and folic acid in adults with essential hypertension: a systematic review and network meta-analysis
Systematic Review BMJ open 2024
B Effect of Vitamin B2 supplementation on migraine prophylaxis: a systematic review and meta-analysis
Meta Analysis Nutritional neuroscience 2022
B Supplementary vitamin E, selenium, cysteine and riboflavin for preventing kwashiorkor in preschool children in developing countries
Systematic Review The Cochrane database of systematic reviews 2010
B Riboflavin supplements for blood pressure lowering in adults.
Cochrane Review The Cochrane database of systematic reviews
B Associations of dietary vitamin B1, vitamin B2, vitamin B6, and vitamin B12 with the risk of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2022
C Prophylaxis of migraine headaches with riboflavin: A systematic review
Systematic Review Journal of clinical pharmacy and therapeutics 2017
C Medium-dose riboflavin as a prophylactic agent in children with migraine: a preliminary placebo-controlled, randomised, double-blind, cross-over trial
Rct Cephalalgia : an international journal of headache 2010
C The efficacy of 2 different phakic intraocular lens implant in keratoconus as an isolated procedure or combined with collagen crosslinking and intra-stromal corneal ring segments: a systematic review and meta-analysis
Meta Analysis International ophthalmology 2023
C Epithelium-off photochemical corneal collagen cross-linkage using riboflavin and ultraviolet a for keratoconus and keratectasia: a systematic review and meta-analysis
Meta Analysis The ocular surface 2014
C Improvement of migraine symptoms with a proprietary supplement containing riboflavin, magnesium and Q10: a randomized, placebo-controlled, double-blind, multicenter trial
Rct The journal of headache and pain 2015
View all evidence for Riboflavin →

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