🟢 84/100

This product is generally safe

  • Niacin: 60mg is 1.7× the Tolerable Upper Intake Level (35mg)
  • Vitamin B6: 150mg is 1.5× the Tolerable Upper Intake Level (100mg)
  • 100% of ingredients have research evidence
D Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 60mg is 1.7× the Tolerable Upper Intake Level (35mg)
⚠️ Vitamin B6: 150mg is 1.5× the Tolerable Upper Intake Level (100mg)

Label Data

1 Capsule(s) Serving Size
60 Servings
Botanical with Nutrients Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

60 mg (300% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.7× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 60mg UL 35mg
150 mg (7500% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.5× (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 150mg UL 100mg
360 mg (90% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 360mg
📊 Market median: 120.0mg (440 products) 📚 187 studies (Tier A: 1, B: 71)
This product: 120mg
30 mg
📊 Market median: 100.0mg (116 products) 📚 15 studies (Tier A: 0, B: 3)
This product: 30mg

Other Ingredients

Microcrystalline Cellulose Rice Flour Ascorbyl Palmitate Silica

Label Claims — Verification

All Other
All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

SUGGESTED USE: As a dietary supplement, take one (1) capsule daily, or as directed by a healthcare professional.

⚠️ Warnings & Precautions

KEEP OUT OF REACH OF CHILDREN.

🧪 Formulation Notes

OL products are free of most allergens such as corn, yeast, barley, wheat, soy, lactose, gluten, citrus, and egg products, as well as added flavorings, sugars, sweeteners, salt, preservatives, salicylates, artificial colors and coatings.

Additional Information

STORE IN A COOL, DRY PLACE.

Researched Ingredients Naturopathic Division

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Made in USA

Product Details

UPC / SKU 7 10013 00102 3
DSLD Entry Date 2012-06-25
Product Type Botanical with Nutrients
Form Capsule
DSLD ID 9943
Data Updated 2026-04-11

Research Evidence

241 Research Sources
55 Avg Quality Score
113 Meta Analysis
75 Systematic Review
32 Rct
11 Clinical Trial
3 Other
3 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016
View all evidence for Niacin →

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