🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade

Product Label

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Label Data

1 Tablet(s) Serving Size
30 Servings
Non-Nutrient/Non-Botanical Product Type
0% Evidence Coverage

Supplement Facts — Evidence Check

📊 Market median: 500.0mg (193 products) 📚 7 studies — no high-quality reviews
This product: 400mg

Other Ingredients

Cellulose Cellulose Gum Methacrylate Polymer Magnesium Stearate Stearic Acid Silica Citric Acid Ascorbic Acid Triethyl Citrate Coloured

Label Claims — Verification

All Other
Structure/Function
All Other (100% of products) Structure/Function (83% of products) Nutrient (6% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Suggested Daily Intake: Take 1 tablet, one time daily, with a meal.

⚠️ Warnings & Precautions

Warning: Individuals with bipolar (manic) depression should not take SAMe unless under professional medical super vision.

If you are pregnant or lactating, consult a health care professional before using this product.

Keep out of reach of children.

🧪 Formulation Notes

BIOVEA's SAMe uses a clinically effective form of SAMe that is 100% vegetarian, gluten-free, and enteric-coated for stability.

BIOVEA's SAMe uses a clinically effective form of SAMe that is 100% vegetarian, gluten-free, and enteric-coated for stability.

Contains No: Milk, egg, fish, crustacean shellfish, tree nuts, wheat, peanuts, soybeans, yeast, corn, glutens, artificial flavours, added sugar, starch or preservatives.

Vegetarian and gluten free

100% vegetarian enteric coated tablets

Additional Information

SAMe: Natural mood support SAMe (S-adenosylymethionine) is a naturally occurring chemical in the body that continually fuels vital body functions, including the nervous system and the liver.

SAMe contributes to the formation of some neurotransmitters, including dopamine and serotonin, helping you to feel better naturally, safely, and effectively.

Store in a cool, dry place.

Guaranteed premium quality

SAMe: Natural mood support Supports nervous system health Promotes healthy liver function

Product Details

DSLD Entry Date 2018-01-25
Product Type Non-Nutrient/Non-Botanical
Form Tablet or Pill
Brand BIOVEA
DSLD ID 82609
Data Updated 2026-04-11

Research Evidence

12 Research Sources
58 Avg Quality Score
8 Meta Analysis
3 Systematic Review
1 Rct
B S-adenosyl-L-methionine for alcoholic liver diseases
Meta Analysis The Cochrane database of systematic reviews 2006
B S-adenosyl methionine (SAMe) for depression in adults
Meta Analysis The Cochrane database of systematic reviews 2016
B Systemic juvenile idiopathic arthritis and adult-onset Still's disease are the same disease: evidence from systematic reviews and meta-analyses informing the 2023 EULAR/PReS recommendations for the diagnosis and management of Still's disease
Meta Analysis Annals of the rheumatic diseases 2024
B SAMe-TT2R2 Score to Predict Time in Therapeutic Range of Vitamin K Antagonists in Asian and Non-Asian patients: A Systematic Review and Meta-analysis
Meta Analysis American journal of cardiovascular drugs : drugs, devices, and other interventions 2024
B S-Adenosylmethionine (SAMe) as an adjuvant therapy for patients with depression: An updated systematic review and meta-analysis
Meta Analysis General hospital psychiatry 2024
B S-adenosyl-L-methionine for alcoholic liver diseases
Systematic Review The Cochrane database of systematic reviews 2001
B WITHDRAWN: S-adenosyl-L-methionine for alcoholic liver diseases
Meta Analysis The Cochrane database of systematic reviews 2015
C S-adenosyl-L-methionine for the treatment of chronic liver disease: a systematic review and meta-analysis
Meta Analysis PloS one 2015
C S-Adenosylmethionine (SAMe) for Liver Health: A Systematic Review
Systematic Review Nutrients 2024
C SAMe-TT2R2 to Predict Clinical Outcomes and Time in Therapeutic Range in Patients on Vitamin K Antagonists: A Systematic Review and Meta-Analysis
Meta Analysis The Annals of pharmacotherapy 2024
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