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QuatreActiv Folate Plus

product on market Capsule Allergy Research Group Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula combines 5-methyltetrahydrofolate and vitamin C, which have strong evidence for supporting methylation and antioxidant functions. Trans-resveratrol and RNA are included for cellular support, though research evidence for these specific components is more limited. The profile maintains a high safety rating.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for QuatreActiv Folate Plus
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
120
Servings
Other Combinations
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin C
600 mg (1000% DV)
500 mcg (125% DV)
1.2× RDA — within safe limits 226 studies (A:10, B:105)
RNA
50 mg
Market median: 167.0mg (311 products) 183 studies (A:0, B:65)

Other Ingredients

Hydroxypropyl Methylcellulose Microcrystalline Cellulose L-Leucine
Claims

Label Claims — Verification

Unverified Nutrient
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use As a dietary supplement, 1 capsule two times daily, or as directed by a healthcare professional.

Formulation Notes

A combination of patented Quatrefolic, the glucosamine salt of 5-methyltetrahydrofolate (5-MTHF), with vitamin C, RNA, and resveratrol, for antioxidant support.

Additional Information

Variations in product color may occur.

Keep in a cool, dry place, tightly capped.

With enhanced antioxidant support

Rev. 005

Metadata

Product Details

UPC / SKU7 13947 76540 5
DSLD Entry Date2017-10-21
Product TypeOther Combinations
FormCapsule
BrandAllergy Research Group
DSLD ID79267
Data Updated2026-04-11
Research

Research Evidence

363
Research Sources
57
Avg Quality
187
Meta Analysis
56
Systematic Review
54
Rct
29
Guideline
26
Clinical Trial
6
Cochrane Review
2
Regulatory Source
1
Other
1
Openfda Safety
A Homocysteine-lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Community-based intervention packages for reducing maternal and neonatal morbidity and mortality and improving neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Folate Intake and Risk of Pancreatic Cancer: A Systematic Review and Updated Meta-Analysis of Epidemiological Studies
Meta Analysis Digestive diseases and sciences 2021 PubMed DOI
A The Association Between the Risk of Hypertensive Disorders of Pregnancy and Folic Acid: A Systematic Review and Meta-Analysis
Meta Analysis Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 2021 PubMed DOI
A A Comparative Study Evaluating the Effectiveness of Folate-Based B Vitamin Intervention on Cognitive Function of Older Adults under Mandatory Folic Acid Fortification Policy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis Nutrients 2024 PubMed DOI
A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025 PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019 PubMed DOI
A Beneficial effects of folic acid supplementation on lipid markers in adults: A GRADE-assessed systematic review and dose-response meta-analysis of data from 21,787 participants in 34 randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2022 PubMed DOI
A Folic acid supplementation and blood pressure: a GRADE-assessed systematic review and dose-response meta-analysis of 41,633 participants
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A Digital tracking, provider decision support systems, and targeted client communication via mobile devices to improve primary health care
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.