Glucosamine Chondroitin Double Strength by CVS Pharmacy — Ingredients, Evidence & Safety

Product Label

Label for Glucosamine Chondroitin Double Strength

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Label Data

3 Caplet(s) Serving Size

20 Servings

Other Combinations Product Type

25% Evidence Coverage

Supplement Facts — Evidence Check

Calories

10 Calorie(s)

Total Carbohydrates

2 Gram(s) (1% DV)

Vitamin C

60 mg (100% DV)

Manganese

2 mg (100% DV)

✅ Within RDA (0.9× RDA of 2.3 mg) 📚 8 studies — no high-quality reviews

RDA 2.3mg This product: 2mg UL 11mg

Sodium

30 mg (1% DV)

Glucosamine HCl

1500 mg

📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)

This product: 1500mg

Chondroitin Sulfate

1200 mg

📊 Market median: 600.0mg (79 products) 📚 24 studies (Tier A: 0, B: 6)

This product: 1200mg

Boron

3 mg

📊 Market median: 3.0mg (58 products) 📚 2 studies — no high-quality reviews

This product: 3mg UL 20mg

Other Ingredients

Cellulose Cellulose Coating Vegetable Magnesium Stearate Titanium Dioxide color Silica natural Palm leaf glaze

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (100% of products) Structure/Function (89% of products) Nutrient (16% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

3 Per day

Directions: For adults, take three (3) caplets daily, preferably one (1) caplet with each meal. As a reminder, discuss the supplements and medications you take with your health care providers.

⚠️ Warnings & Precautions

Keep out of reach of children.

Tamper resistant: Do not use if seal under cap is broken or missing.

Contains shellfish (shrimp, crab, lobster, crayfish) ingredients.

Warnings: If you are pregnant, nursing, taking any medications, including blood thinners, or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

🧪 Formulation Notes

Contains shellfish (shrimp, crab, lobster, crayfish) ingredients.

No yeast, wheat, gluten, milk or milk derivatives, lactose, sugar, preservatives, soy, artificial flavor.

Additional Information

Store at room temperature and avoid excessive heat.

Individual results may vary.

CVS Quality money back guarantee

Actual size

Prod. No. 6645 B44943 08C

Joint health

Supports flexibility & range of motion

Glucosamine and chondroitin help support and maintain healthy cartilage. Glucosamine and chondroitin are popular ingredients used to support joint function and mobility.

Product Details

UPC / SKU 0 50428 00062 5

DSLD Entry Date 2016-09-22

Product Type Other Combinations

Form Other (e.g. tea bag)

Brand CVS Pharmacy

DSLD ID 64331

Data Updated 2026-04-11

Research Evidence

39 Research Sources

50 Avg Quality Score

20 Rct

9 Meta Analysis

4 Clinical Trial

3 Systematic Review

1 Regulatory Source

1 Openfda Safety

B Interventions for the management of temporomandibular joint osteoarthritis

Systematic Review The Cochrane database of systematic reviews 2012

PubMed DOI Cochrane

B Glucosamine therapy for treating osteoarthritis

Meta Analysis The Cochrane database of systematic reviews 2005

PubMed Cochrane

B Chondroitin for osteoarthritis

Meta Analysis The Cochrane database of systematic reviews 2015

PubMed DOI Cochrane

B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis

Meta Analysis Archives of orthopaedic and trauma surgery 2023

PubMed DOI

B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis

Rct The New England journal of medicine 2006

PubMed

B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review

Systematic Review International journal of molecular sciences 2023

PubMed DOI

B Scientific Opinion on glucosamine and joint health

Regulatory Source EFSA Journal 2009

DOI

B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis

Meta Analysis Computational and mathematical methods in medicine 2022

PubMed DOI

B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib

Rct Annals of the rheumatic diseases 2016

PubMed DOI

B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials

Meta Analysis Journal of orthopaedic surgery and research 2018

PubMed DOI

View all evidence for Glucosamine →