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Optimized Resveratrol with Nicotinamide Riboside

product on market Capsule Life Extension Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 67% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

This formula combines Trans-Resveratrol and Nicotinamide Riboside, which are supported by moderate evidence for promoting cellular energy and NAD+ levels. Quercetin and Fisetin are included as senolytic agents to target aging cells, though human clinical data for these specific effects remains limited. The blend incorporates fruit extracts to provide additional antioxidant support.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Optimized Resveratrol with Nicotinamide Riboside
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Vegetarian Capsule(s)
Serving Size
Other Combinations
Product Type
67%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 167.0mg (311 products) 183 studies (A:0, B:65)
150 mg
Market median: 500.0mg (283 products) 174 studies (A:0, B:62)
Market median: 300.0mg (26 products) 7 studies (A:0, B:1)
Red Grape (fruit) and Wild Blueberry (fruit) blend
40 mg
Fisetin
10 mg
Market median: 167.0mg (311 products) 183 studies (A:0, B:65)

Other Ingredients

Vegetable Cellulose Microcrystalline Cellulose Silica Vegetable Stearate Maltodextrin
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Read the entire label and follow the directions carefully prior to use. DIRECTIONS: Take one (1) capsule daily with or without food, or as recommended by a healthcare practitioner.

Warnings & Precautions

CAUTION: If you are taking anti-coagulant or anti-platelet medications, or have bleeding disorder, consult your healthcare provider before taking this product.

WARNINGS: -Keep out of reach of children.

-Do not exceed recommended dose. -Do not purchase if outer seal is broken or damaged.

-When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

Formulation Notes

Non-GMO

Additional Information

Scan for product info

Q02031A

Advanced Defense Against Cellular Aging*

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

Store tightly closed in a cool, dry place.

Metadata

Product Details

UPC / SKU7 37870 20313 1
DSLD Entry Date2016-06-24
Product TypeOther Combinations
FormCapsule
DSLD ID60754
Data Updated2026-04-11
Research

Research Evidence

10
Research Sources
49
Avg Quality
8
Rct
1
Systematic Review
1
Clinical Trial
B Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults
Rct Nature communications 2018 PubMed DOI
C The effects of NAD+ precursor (nicotinic acid and nicotinamide) supplementation on weight loss and related hormones: a systematic review and meta-regression analysis of randomized controlled trials
Systematic Review Frontiers in nutrition 2023 PubMed DOI
C Effect of nicotinamide riboside on airway inflammation in COPD: a randomized, placebo-controlled trial.
Rct Nature aging PubMed DOI
C Safety and Metabolism of Long-term Administration of NIAGEN (Nicotinamide Riboside Chloride) in a Randomized, Double-Blind, Placebo-controlled Clinical Trial of Healthy Overweight Adults
Rct Scientific reports 2019 PubMed DOI
C Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD+ Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures
Rct Cell reports 2019 PubMed DOI
C Oral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin
Rct Aging cell 2023 PubMed DOI
C Nicotinamide riboside with pterostilbene (NRPT) increases NAD+ in patients with acute kidney injury (AKI): a randomized, double-blind, placebo-controlled, stepwise safety study of escalating doses of NRPT in patients with AKI
Rct BMC nephrology 2020 PubMed DOI
C Clinical Trial of Niagen to Examine Recovery in People With Persistent Cognitive and Physical Symptoms After COVID-19
Clinical Trial ClinicalTrials.gov 2021
C A randomized placebo-controlled trial of nicotinamide riboside and pterostilbene supplementation in experimental muscle injury in elderly individuals.
Rct JCI insight PubMed DOI
C Nicotinamide Riboside Supplementation Benefits in Patients With Werner Syndrome: A Double-Blind Randomized Crossover Placebo-Controlled Trial.
Rct Aging cell PubMed DOI
View all evidence for Nicotinamide Riboside →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.